Effects of acute thermal stress on the immune system of the Northern Bobwhite (Colinus virginianus)
Effects of acute thermal stress on the immune system of the Northern Bobwhite (Colinus virginianus)
复制标题
作者：
Dabbert, CB;Lochmiller, RL;Teeter, RG
我们测试了这样的假设：北山白猫（Colinus virginianus）暴露于急性温度应激源会损害其免疫系统功能和对疾病的抵抗力。鸡被随机分配到热中性（恒定 21 摄氏度）、冷应激（24 小时内从 3.6 到 -20 摄氏度循环）或热应激（24 小时内从 30.8 到 39.0 摄氏度循环）治疗，连续四天。在第 5 天，使用一组检测评估每只鸡的免疫能力，包括对 3 型多杀性巴斯德氏菌攻击的抗性测量。热应激源对脾脏质量或细胞介导和体液免疫的测量没有影响。北山白犬对多杀性巴氏杆菌的抗病性不受热应激的影响，但在冷应激后增强。冷应激可能增加了吞噬白细胞的活性，这对于鸟类抵抗细菌病原体非常重要。淋巴细胞数量的随之减少表明，在冷应激期间，对病毒病原体的抵抗力受到损害。
We tested the hypothesis that exposure of Northern Bobwhites (Colinus virgi nianus) to acute temperature stressors impairs their immune-system function and resistance to disease. Birds were randomly assigned to either a thermoneutral (constant 21 degrees C), cold-stress (cycled from 3.6 to -20 degrees C over 24 h), or heat-stress (cycled from 30.8 to 39.0 degrees C over 24 h) treatment for four consecutive days. Immunocompetence of each bird was evaluated on day 5 using a panel of assays, including a measure of resistance to a Pasteurella multocida Type 3 challenge. Neither thermal stressor had an influence on spleen mass or measures of cell-mediated and humoral immunity. Disease resistance of Northern Bobwhites to P. multocida was not influenced by heat stress but increased following cold stress. Cold stress may have increased the activity of phagocytic leukocytes, which are important in resistance of birds to bacterial pathogens. A concomitant decrease in lymphocyte numbers suggested that resistance to viral pathogens was compromised during cold stress.