Cortical surface-based analysis - I. Segmentation and surface reconstruction

Cortical surface-based analysis - I. Segmentation and surface reconstruction
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DOI:
10.1006/nimg.1998.0395
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发表时间:
1999-02-01
期刊:
影响因子:
5.7
通讯作者:
Sereno, MI
Sereno, MI
中科院分区:
医学1区
文献类型:
--
作者:
Dale, AM;Fischl, B;Sereno, MI

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大脑皮层的一些特性,包括它的柱状和层状组织,以及皮质区域的地形组织,只有在皮质表面的内在二维结构的背景下才能被正确地理解。为了研究人类的这种皮质特性,有必要获得单个受试者的皮质表面的准确和明确的表示。在这里,我们描述了一套获得皮质表面准确重建的自动化程序,这些程序已应用于100多名受试者的数据,几乎不需要人工干预。展开和平整皮质表面的自动化程序在一篇配对论文中描述。这些程序允许在脑功能成像中常规使用基于皮质表面的分析和可视化方法。(C)1999年学术出版社。
Several properties of the cerebral cortex, including its columnar and laminar organization, as well as the topographic organization of cortical areas, can only be properly understood in the context of the intrinsic two-dimensional structure of the cortical surface. In order to study such cortical properties in humans, it is necessary to obtain an accurate and explicit representation of the cortical surface in individual subjects. Here we describe a set of automated procedures for obtaining accurate reconstructions of the cortical surface, which have been applied to data from more than 100 subjects, requiring little or no manual intervention. Automated routines for unfolding and flattening the cortical surface are described in a companion paper. These procedures allow for the routine use of cortical surface-based analysis and visualization methods in functional brain imaging. (C) 1999 Academic Press.