Relationship between age, prostate volume, prostate-specific antigen, symptom score and uroflowmetry in men with lower urinary tract symptoms - Does prostate size matter?

Relationship between age, prostate volume, prostate-specific antigen, symptom score and uroflowmetry in men with lower urinary tract symptoms - Does prostate size matter?
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DOI:
10.1080/00365590310014760
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发表时间:
2003-01-01
影响因子:
--
通讯作者:
Dahlstrand, C
Dahlstrand, C
中科院分区:
其他
文献类型:
--
作者:
Vesely, S;Knutson, T;Dahlstrand, C

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目的:目的探讨良性前列腺肥大(BPE)下尿路症状(LUTS)患者不同诊断指标与年龄的关系,并比较正常人、健康人和LUTS患者的前列腺生长曲线。(平均年龄70.2岁;范围45-91岁)由于BPE的LUTS分为7个年龄组,并进行回顾性分析。所有患者均接受标准评估,包括国际前列腺症状评分(IPSS)、直肠指检、尿流率测定、前列腺特异性抗原(PSA)水平测定和经直肠超声检查。结果:前列腺体积平均为4 0.1(± 2 3.9)cm 3,前列腺特异性抗原(PSA)浓度平均为3.9(± 4.2)ng/ml。两个值分别从27.5 ml和1.5 ng/ml逐渐增加,
Objectives: To estimate the relationship between age and the values of different diagnostic tests in men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic enlargement (BPE) and to compare prostate growth curves between the normal population sample, healthy men and men with LUTS.Material and Methods: A series of 354 men (mean age 70.2 years; range 45-91 years) with LUTS due to BPE were stratified into seven age groups and reviewed retrospectively. All patients underwent a standard evaluation, involving determination of the International Prostate Symptom Score (IPSS), digital rectal examination, uroflowmetry, determination of the prostate-specific antigen (PSA) level and transrectal ultrasonography. Descriptive statistics were used to describe all the variables and Spearman's correlation test was used to evaluate the relationships between them.Results: The mean prostate volume was 40.1 (+/-23.9) cm 3 and mean PSA concentration 3.9 (+/-4.2) ng/ml. Both values increased progressively from 27.5 ml and 1.5 ng/ml, respectively in the