Large artery intracranial occlusive disease - A large worldwide burden but a relatively neglected frontier
Large artery intracranial occlusive disease - A large worldwide burden but a relatively neglected frontier
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DOI：
10.1161/strokeaha.107.505776
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发表时间：
2008-08-01
期刊：
影响因子：
8.3
通讯作者：
Pandey, Dilip K.
中科院分区：
文献类型：
--
作者：
Gorelick, Philip B.;Wong, Ka Sing;Pandey, Dilip K.
背景和目的-大动脉颅内闭塞性疾病（LAICOD）是一种常见且重要的卒中亚型。在这篇评论中，我们回顾了LAICOD.Summary的流行病学方面，LAICOD已成为世界范围内最常见的卒中亚型，并与卒中复发的高风险相关。已经提出了一些假设来解释因果关系，其中包括传统的心血管危险因素，高血容量状态和遗传异常等因素。治疗方法，如抗血栓治疗，血运重建程序，和反搏设备持有promise.Conclusions-LAICOD构成了一个重大的中风问题，在世界范围内，可能是最常见的中风亚型。这种疾病的病因和治疗仍然不明确。需要国际合作来汇集集体知识并开发确定性研究，以更好地了解LAICOD的病因和治疗方法。
Background and Purpose-Large artery intracranial occlusive disease (LAICOD) is a common and important stroke subtype. In this commentary, we review key epidemiological aspects of LAICOD.Summary of Review-LAICOD has emerged as the most common stroke subtype worldwide and is associated with a high risk of recurrent stroke. Hypotheses have been proposed to explain causation, which include such factors as traditional cardiovascular risk factors, high blood volume states, and genetic abnormalities. Approaches to treatment such as antithrombotic therapies, revascularization procedures, and counterpulsation devices hold promise.Conclusions-LAICOD poses a major stroke problem worldwide and is likely the most common stroke subtype. The etiology and treatment of this disorder remain poorly defined. International collaborations are needed to pool collective knowledge and develop definitive studies to better understand causation and treatment of LAICOD.