Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
Expression of transforming growth factor beta 2 RNA during murine embryogenesis.
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发表时间：
1989-08
期刊：
影响因子：
4.6
通讯作者：
R. Pelton;S. Nomura;H. Moses;B. Hogan
中科院分区：
文献类型：
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作者：
R. Pelton;S. Nomura;H. Moses;B. Hogan
我们研究了转化生长因子β 2（TGF β 2）RNA在小鼠胚胎中的时空表达。至产后3天（p. p.）通过原位杂交分析。TGF β 2 RNA在多种组织中表达，包括骨、软骨、肌腱、肠、血管、皮肤和胎儿胎盘，并且通常在这些组织的间充质组分中发现。TGF β 2 RNA的表达在发育过程中以与基因产物在介导间质-上皮相互作用中的作用一致的方式变化。
We have studied the temporal and spatial expression of transforming growth factor beta 2 (TGF beta 2) RNA in mouse embryos from 10.5 days post coitum (p.c.) to 3 days post partum (p.p.) by in situ hybridization analysis. TGF beta 2 RNA is expressed in a variety of tissues including bone, cartilage, tendon, gut, blood vessels, skin and fetal placenta, and is in general found in the mesenchymal component of these tissues. The expression of TGF beta 2 RNA changes during development in a manner consistent with a role for the gene product in mediating mesenchymal-epithelial interactions.