Palladium-catalyzed glycal imidate rearrangement: formation of alpha- and beta-N-glycosyl trichloroacetamides.
Palladium-catalyzed glycal imidate rearrangement: formation of alpha- and beta-N-glycosyl trichloroacetamides.
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钯催化的糖基亚氨酸重排：α-和β-N-糖基三氯乙酰胺的形成。
DOI：
10.1021/ol701778z
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发表时间：
2007
期刊：
影响因子：
5.2
通讯作者：
Hien M. Nguyen
中科院分区：
文献类型：
--
作者：
Jaemoon Yang;G. J. Mercer;Hien M. Nguyen
发展了一种新的钯催化立体选择性合成α-和β-N-糖基三氯乙酰胺的方法。异头碳的α-和β-选择性取决于钯-配体催化剂的性质。虽然阳离子钯（II）促进α-选择性，但中性钯（II）有利于β-选择性。
A novel palladium(II)-catalyzed stereoselective synthesis of alpha- and beta-N-glycosyl trichloroacetamides has been developed. The alpha- and beta-selectivity at the anomeric carbon depends on the nature of the palladium-ligand catalyst. While the cationic palladium(II) promotes the alpha-selectivity, the neutral palladium(II) favors the beta-selectivity.