4-Chloro-2-azaadamantane N-Oxyl (4-Cl-AZADO): A Readily Preparable Organocatalyst for NOx Co-catalyzed Aerobic Alcohol Oxidation
4-Chloro-2-azaadamantane N-Oxyl (4-Cl-AZADO): A Readily Preparable Organocatalyst for NOx Co-catalyzed Aerobic Alcohol Oxidation
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4-Chloro-2-azaadamantane N-Oxyl (4-Cl-AZADO)：一种易于制备的有机催化剂，用于 NOx 共催化好氧醇氧化
DOI：
10.1002/ajoc.202300031
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发表时间：
2023
影响因子：
2.7
通讯作者：
Yoshiharu Iwabuchi
中科院分区：
文献类型：
--
作者：
Shota Nagasawa;Yusuke Sasano;Yoshiharu Iwabuchi
4-氯-2-氮杂金刚烷N-氧基（4-Cl-AZADO）是一种高效的有机催化剂，在NOx作为助催化剂的存在下，它可以催化醇类的有氧氧化反应.该有机催化剂由2-金刚烷酮经五步反应合成，与许多已报道的硝酰基自由基催化剂相比，具有较高的活性。
Concise synthesis and structure‐activity relationships study of 4‐substituted 2‐azaadamantaneN‐oxyls reveals that 4‐chloro‐2‐azaadamantaneN‐oxyl (4‐Cl‐AZADO) is an efficient organocatalyst toward the aerobic oxidation of alcohols in the presence of NOxas a co‐catalyst. The organocatalyst was easily synthesized from 2‐adamantanone in five steps, and it showed high activity compared with many previously reported nitroxyl radical catalysts.