A Bibliometric Analysis of Mesenchymal Stem Cell-Derived Exosomes in Acute Lung Injury/Acute Respiratory Distress Syndrome from 2013 to 2022.
A Bibliometric Analysis of Mesenchymal Stem Cell-Derived Exosomes in Acute Lung Injury/Acute Respiratory Distress Syndrome from 2013 to 2022.
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DOI：
10.2147/dddt.s415659
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发表时间：
2023
影响因子：
4.8
通讯作者：
Yang, Hao
中科院分区：
文献类型：
--
作者：
Zhou, Wenyu;Hu, Song;Wu, Yutong;Xu, Huan;Zhu, Lina;Deng, Huimin;Wang, Sheng;Chen, Yuanli;Zhou, Huanping;Lv, Xin;Li, Quanfu;Yang, Hao
间充质干细胞来源的Exosome(MSC-Exosome)可有效改善急性肺损伤和急性呼吸窘迫综合征(ALI/ARDS)引起的全身炎症反应，调节全身免疫紊乱，帮助损伤细胞修复。本研究的目的是全面了解ALI/ARDS中MSC-exosome的研究现状和趋势。采用文献计量学软件Bibliometrix、Citesspace和VOS-Viewer对数据进行计量分析。根据收集的数据，我们分析了与冠状病毒病2019(新冠肺炎)相关的世界趋势、国家分布、机构贡献、最相关的期刊和作者、研究热点和研究热点。中国发表的论文数量最多，而美国的H指数和引文量最高。中国和美国在这一研究领域都有很高的影响。在MSC-exosome和ALI/ARDS领域发表的论文数量最多，主要来自加利福尼亚大学系统。干细胞研究与治疗在这一领域发表的论文数量最多。贡献最大的作者是李智伟，朱YG在《干细胞》上发表了一篇被当地引文得分最高的文章。出现频率最高的关键词和最新的研究热点分别是“NF-κB”和“冠状病毒病2019年”。此外，我们的文献计量学分析结果表明，MSC-exosome干预和治疗可以有效地减轻ALI/ARDS引起的炎症反应。我们的文献计量学研究表明，美国和中国在这一领域具有很强的影响力。新冠肺炎诱导的ALI/ARDS已成为研究热点。
Mesenchymal stem cell-derived exosomes (MSC-exosomes) have been found to effectively improve the systemic inflammatory response caused by acute lung injury and acute respiratory distress syndrome (ALI/ARDS), regulate systemic immune disorders, and help injured cells repair. The purpose of this study was to take a holistic view of the current status and trends of MSC-exosomes research in ALI/ARDS. Bibliometrix, Citespace and VOSviewer software were used for bibliometric analysis of the data. We analysed the world trends, country distribution, institution contribution, most relevant journals and authors, research hotspots, and research hotspots related to Coronavirus Disease 2019 (COVID-19) based on the data collected. China possessed the largest number of publications, while the USA had the highest H-index and the number of citations. Both China and the USA had a high influence in this research field. The largest number of publications in the field of MSC-exosomes and ALI/ARDS were mainly from the University of California system. Stem Cell Research & Therapy published the largest number of papers in this scope. The author with the greatest contribution was LEE JW, and ZHU YG published an article in Stem Cell with the highest local citation score. The most frequent keyword and the latest research hotspot were “NF-κB” and “Coronavirus Disease 2019”. Furthermore, our bibliometric analysis results demonstrated that MSC-exosomes intervention and treatment can effectively alleviate the inflammatory response caused by ALI/ARDS. Our bibliometric study suggested the USA and China have a strong influence in this field. COVID-19-induced ALI/ARDS had become a hot topic of research.