Using Caenorhabditis elegans to assess the ecological health risks of heavy metals in soil and sediments around Dabaoshan Mine, China
Using Caenorhabditis elegans to assess the ecological health risks of heavy metals in soil and sediments around Dabaoshan Mine, China
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利用秀丽隐杆线虫评估中国大宝山矿区土壤和沉积物中重金属的生态健康风险
DOI：
10.1007/s11356-021-16807-w
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发表时间：
2021-10
影响因子：
5.8
通讯作者：
Yong Liang
中科院分区：
文献类型：
--
作者：
Xin Li;Qingqing Yang;Ling Wang;Chuxin Song;Lufeng Chen;Jie Zhang;Yong Liang
重金属污染是一个全球性的环境问题，与重金属相关的潜在风险正在增加。中国南部最大的多金属矿山--大宝山矿在采矿活动中产生的酸性矿井水对当地居民有害。迫切需要对这一污染地区的生态和人类健康风险进行详细的区域调查。本研究采集了尾矿废水和凡东水库沿流方向的8个底泥和农田样品，采用电感耦合等离子体质谱对样品中多种重金属的含量进行了测定。以秀丽线虫的不同终点为参照，进一步评价了样品中水溶性提取物的生物毒性。用偏最小二乘回归估计特定重金属与生物毒性之间的关系。结果表明，大宝山矿区重金属的风险很高(潜在生态风险指数 = 为721.53)，且与地理位置有关。在这些样本中，砷(As)对成年人的致癌风险(当人们接触致癌污染物时引发致癌疾病或伤害的概率)超过标准值1 × 10−4，表明As对成年人具有很高的致癌风险，而儿童的非致癌效应的高风险(人类接触非致癌污染物的危害程度)与铅暴露(危害指数 = 1.24)有关。此外，沉积物和农田土壤浸出物中较高浓度的重金属易在水循环中分布，对线虫的存活率和生长有抑制作用。与氧化应激相关的基因表达和酶活性增加，与细胞凋亡和金属硫蛋白相关的基因也受到影响。总之，化学分析和生物测定的结果为大宝山矿区土壤和沉积物提取物的毒性提供了证据，并为大宝山矿区周围重金属污染的控制和修复提供了依据。
Heavy metal pollution is a global environmental problem, and the potential risks associated with heavy metals are increasing. The acid mine drainage (AMD) which is generated by mining activities at Dabaoshan Mine, the largest polymetallic mine in southern China, is harmful to local residents. A detailed regional survey of the ecological and human health risks of this polluted area is urgently needed. In this study, eight sediments and farmland samples were collected along the flow direction of tailing wastewater and Fandong Reservoir; the content of multiple heavy metals in these samples was determined by inductively coupled plasma mass spectrometry. The biological toxicity of water-soluble extracts from the samples was further assessed by referring to different endpoints of Caenorhabditis elegans (C. elegans). The relationship between specific heavy metals and biological toxicity was estimated by partial least squares regression. The results indicated that the risk of heavy metals in Dabaoshan mining area was very high (potential ecological risk index = 721.53) and was related to geographical location. In these samples, the carcinogenic risk (the probability that people are induced carcinogenic diseases or injuries when exposed to carcinogenic pollutants) of arsenic (As) for adults exceeded the standard value 1 × 10−4 and indicated that As presented a high carcinogenic risk to adults, while the high risk of non-carcinogenic effects (the hazard degree of human exposure to non-carcinogenic pollutants) in children was related to lead exposure (hazard index = 1.24). In addition, the heavy metals at high concentration in the water-soluble fraction of sediment and farmland soil extracts, which might easily distribute within the water cycle, inhibited the survival rate and growth of C. elegans. Gene expression and enzymatic activity related to oxidative stress were increased and genes related to apoptosis and metallothionein were also affected. In conclusion, the results of chemical analysis and biological assays provided evidence on the toxicity of soil and sediment extracts in the Dabaoshan mining area and advocated the control and remediation of heavy metal pollution around Dabaoshan Mine.
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DOI：
10.1016/j.scitotenv.2017.08.121
发表时间：
2018-02
期刊：
The Science of the total environment
影响因子：
--
作者：
M. Hagner;M. Romantschuk;O. Penttinen;A. Egfors;C. Marchand;A. Augustsson
通讯作者：
M. Hagner;M. Romantschuk;O. Penttinen;A. Egfors;C. Marchand;A. Augustsson
影响因子：
3.7
作者：
Zhuang P;Lu H;Li Z;Zou B;McBride MB
通讯作者：
McBride MB
影响因子：
13.6
作者：
Li, Siyue;Zhang, Quanfa
通讯作者：
Zhang, Quanfa
影响因子：
5.7
作者：
Jian-min Zhou;Z. Dang;M. Cai;Cong-Qiang Liu
通讯作者：
Jian-min Zhou;Z. Dang;M. Cai;Cong-Qiang Liu
影响因子：
8.8
作者：
Jiang, Yanxue;Chao, Sihong;Cao, Hongbin
通讯作者：
Cao, Hongbin