Clinical profile and Japanese encephalitis viral serological screening of children with acute encephalitis in Varanasi, India.
Clinical profile and Japanese encephalitis viral serological screening of children with acute encephalitis in Varanasi, India.
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印度瓦拉纳西急性脑炎儿童的临床概况和日本脑炎病毒血清学筛查。
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发表时间：
1998
影响因子：
2
通讯作者：
R. Durmaz
中科院分区：
文献类型：
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作者：
B. Durmaz;Cengiz Yakinci;M. Köroğlu;M. Rafiq;R. Durmaz
采用酶免疫法测定了90例7 ~ 11岁寄生虫感染儿童和24例健康儿童血清总IgE水平。在90名儿童中，46名感染了贾第虫，26名感染了蛲虫，18名同时感染了这两种寄生虫。结果表明，寄生虫感染儿童血清总IgE平均值为170.17 ± 27.76IU/ml，其中24例高于100 IU/ml，5例高于1000 IU/ml。对照组儿童的IgE平均值为39.41 ±14.68 IU/ml。两组间IgE水平有显著性差异（P< 0.01）。兰氏贾第鞭毛虫感染的患儿用甲硝唑15-20 mg/kg/d，连用10 d，虫性肠球菌感染的患儿用甲苯咪唑100 mg/d，混合感染的患儿用甲硝唑联合甲苯咪唑治疗。在开始治疗15天后，73名儿童重新检查寄生虫和IgE水平。本组未发现寄生虫。治疗前后IgE均值分别为145.12±28.19和76.56 ± 19.63IU/ml。治疗前后血清IgE水平差异有显著性（P< 0.001）。[Turgut Ozal医学中心杂志1996;3（4）：332-335]
Concentrations of total serum IgE in 90 parasitized children and 24 healthy control children between 7 and 11 years old were measured using enzyme immunoassay. Of 90 children, 46 were infected with Giardia lamblia, 26 with Enterobius vermicularis, and 18 with both of these parasites. The overall mean value of IgE in parasitized children was 170.17 ± 27.76 IU/ml, almost 24 of children had an IgE value of more than 100 IU/ml, and 5 showed a value of more than 1000 IU/ml. The mean value of IgE in control children was 39.41 ±14.68 IU/ml. IgE levels showed a significant difference between those two groups (p< 0.01). Children infected with G.lamblia were treated with metronidazole (15-20 mg/kg/day for 10 days), while those with E.vermicularis were treated with single dose mebendazole (100 mg/day), and in children having mixed G.lamblia and E.vermicularis infection, combination of metronidazole with mebendazole was used in therapy. After 15 days of the onset therapy, 73 children were reexamined for parasites and IgE levels. No parasite was found in this group. The mean value of IgE was found to be 145.12±28.19 and 76.56 ±19.63 IU/ml before and after therapy, respectively. There was significant difference in IgE concentrations between before and after therapy (p< 0.001). [Journal of Turgut Ozal Medical Center 1996;3(4):332-335]