Nosocomial infections caused by community-associated methicillin-resistant Staphylococcus aureus in Colombia

Nosocomial infections caused by community-associated methicillin-resistant Staphylococcus aureus in Colombia
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DOI:
10.1016/j.ajic.2009.05.013
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发表时间:
2010-05-01
影响因子:
4.9
通讯作者:
Vanegas, Natasha
Vanegas, Natasha
中科院分区:
医学3区
文献类型:
--
作者:
Alvarez, Carlos Arturo;Yomayusa, Nancy;Vanegas, Natasha

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Background: Community-associated methicillin-resistant Staphylococcus aureus strains (CA-MRSA) have emerged as the causative agent of health care-associated infections.Methods: An observational and prospective study was carried out in 5 hospitals in Bogota, Colombia; severe MRSA infections were identified, and their origin led to classification as health care-associated (HA-MRSA), community-associated, or nosocomial infections. MRSA isolates were analyzed by SCCmec, pulsed-field gel electrophoresis, multilocus sequence typing, and virulence factors.Results: Twenty-six (10.4%) CA-MRSA nosocomial infection-causing strains (eg, USA300) were detected in 250 MRSA infection isolates in mainly primary bacteremia and surgical site infections. The mortality related to nosocomial infection by CA-MRSA was 27%.Conclusion: The presence of nosocomial infection by CA-MRSA in Colombia was confirmed.