Optical coherence tomography modeling incorporating scattering, absorption, and multiple reflections
Optical coherence tomography modeling incorporating scattering, absorption, and multiple reflections
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DOI：
10.1364/josaa.377121
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发表时间：
2020-03-01
影响因子：
1.9
通讯作者：
Hinckley, Steven
中科院分区：
文献类型：
--
作者：
Guan, Anna;Richardson, Steven;Hinckley, Steven
建立了一个直接散射光学相干层析正演模型，模拟了理想光源和实际光源在任意给定样品结构上的A扫描。以前的模型忽略了界面层的吸收、散射和多次反射，因此发展了两个扩展的模型来研究这些过程的影响。第一个模型使用Beer-Lambert定律来包含吸收和散射光学过程，第二个模型使用递归形式来模拟多次反射。这些模型是在代表多层皮肤样本的结构上进行测试的。结果表明，吸收和散射过程对模拟A扫描中的峰高有显著影响。相反，多次反射的合并对这些峰的高度影响很小。上述两种工艺都不会对与层间样品界面相关的A扫描峰的位置产生任何影响。(C)2020年美国光学学会
A direct scattering optical coherence tomography forward model was developed to simulate A-scans for both idealized and real light sources on an arbitrary given sample structure. Previous models neglected absorption, scattering, and multiple reflections at interfacial layers, and so two extended models were developed to investigate the impact of these processes. The first model uses the Beer-Lambert law to incorporate both absorption and scattering optical processes, and the second model uses a recursive form to model multiple reflections. These models were tested on a structure representative of a multilayered skin sample. The results show that the absorption and scattering processes have significant impact on the height of the peaks in the simulated A-scans. Conversely, the incorporation of multiple reflections has very little impact on the height of these peaks. Neither of t he above processes has any impact on the locations of the A-scan peaks, which are associated with the sample interfaces between layers. (C) 2020 Optical Society of America