An open source ion gate pulser for ion mobility spectrometry
An open source ion gate pulser for ion mobility spectrometry
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DOI：
10.1007/s12127-017-0223-x
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发表时间：
2017-12-01
影响因子：
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通讯作者：
Clowers, Brian H.
中科院分区：
文献类型：
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作者：
Garcia, Luke;Saba, Carolyn;Clowers, Brian H.
除了离子源，离子迁移谱仪基本上由漂移室、离子门、脉冲电子设备和用于放大和记录离子信号的机构组成。从历史上看，这些挑战的解决方案都是定制的，很少完全复制。对于IMS研究界来说，很少有详细的资源明确详细介绍离子迁移系统的构建和操作。为了解决这一知识差距，我们概述了漂移管离子迁移率系统的关键方面之一，离子门脉冲发生器的解决方案。Bradbury-Nielsen或廷德尔离子门在几乎每一个研究级和商业IMS系统中都有。虽然概念上很简单，但这些栅极结构通常需要定制的高压浮置电子器件。在本报告中，我们详细介绍了一种支持WiFi的、基于以太网的脉冲发生器设计的操作和性能特征，该设计使用锂聚合物电池，不需要高压隔离变压器。目前，该电路的每个输出都跟随一个TTL信号，上升和下降时间约为20 ns，脉冲高达+/- 200 V，并使用光纤进行完全隔离。提供了详细的原理图和源代码，以使持续使用强大的脉冲电子，简化实验工作，为未来的比较。
Excluding the ion source, an ion mobility spectrometer is fundamentally comprised of drift chamber, ion gate, pulsing electronics, and a mechanism for amplifying and recording ion signals. Historically, the solutions to each of these challenges have been custom and rarely replicated exactly. For the IMS research community few detailed resources exist that explicitly detail the construction and operation of ion mobility systems. In an effort to address this knowledge gap we outline a solution to one of the key aspects of a drift tube ion mobility system, the ion gate pulser. Bradbury-Nielsen or Tyndall ion gates are found in nearly every research-grade and commercial IMS system. While conceptually simple, these gate structures often require custom, high-voltage, floating electronics. In this report we detail the operation and performance characteristics of a wifi-enabled, MOSFET-based pulser design that uses a lithium-polymer battery and does not require high voltage isolation transformers. Currently, each output of this circuit follows a TTL signal with similar to 20 ns rise and fall times, pulses up to +/- 200 V, and is entirely isolated using fiber optics. Detailed schematics and source code are provided to enable continued use of robust pulsing electronics that ease experimental efforts for future comparison.