Human gene therapy vectors derived from feline lentiviruses
Human gene therapy vectors derived from feline lentiviruses
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DOI：
10.1016/j.vetimm.2008.01.009
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发表时间：
2008-05-15
影响因子：
1.8
通讯作者：
Poeschla, Eric M.
中科院分区：
文献类型：
--
作者：
Barraza, Roman A.;Poeschla, Eric M.
慢病毒载体可用于将基因转移到分裂和非分裂细胞。猫免疫缺陷病毒（FIV）载体以良好的效率感染大多数人类细胞类型，并可能在临床基因治疗应用中具有优势。本文综述了FIV载体系统的开发和完善方面的重要进展。(C)2008 Elsevier B.V.保留所有权利。
Lentiviral vectors are useful for gene transfer to dividing and nondividing cells. Feline immunodeficiency virus (FIV) vectors transduce most human cell types with good efficiency and may have advantages for clinical gene therapy applications. This article reviews significant progress in the development and refinement of FIV vector systems. (C) 2008 Elsevier B.V. All rights reserved.