Development of cardiovascular responses in the kitten.
Development of cardiovascular responses in the kitten.
复制标题
小猫心血管反应的发展。
DOI：
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发表时间：
1962
影响因子：
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通讯作者：
I. Young
中科院分区：
文献类型：
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作者：
E. A. Hutchinson;C. Percival;I. Young
在麻醉的小猫中，平均动脉压和脉压在生命的前 6 周内翻倍；记录的心率与成年猫相同，在此期间没有变化。血管舒缩交感系统在出生后4天内活跃：既有强直活动，如颈动脉闭塞后动脉压升高所证明，也有窒息时压力升高；颈动脉窦-心脏中枢机制对出生时动脉压升高做出反应。所有这些反应都随着年龄的增长而增加，但到生命第六周时尚未达到成人活动水平。直到 4 周龄时，颈动脉窦-心脏中枢机制才对血压下降做出反应。婴儿心脏显然对乙酰胆碱的直接作用更敏感，而外周血管的敏感性相对低于成人。
In anaesthetized kittens the mean arterial pressure and the pulse pressure double during the first 6 weeks of life; the heart rates recorded were the same as in the adult cat and did not change during this period. The vasomotor sympathetic system was active within 4 days of birth: there was both tonic activity, as demonstrated by a rise in arterial pressure after carotid occlusion, and a rise in pressure during asphyxia; the carotid sinus-cardiac centre mechanism responded to a rise in arterial pressure at birth. All these responses increased with age but had not reached adult activity by the 6th week of life. The carotid sinus-cardiac centre mechanism did not respond to a fall in blood pressure until 4 weeks of age. The infant heart was apparently more sensitive to the direct action of acetylcholine and the peripheral blood vessels relatively less sensitive than in the adult.