Femtosecond laser versus manual dissection for top hat penetrating keratoplasty
Femtosecond laser versus manual dissection for top hat penetrating keratoplasty
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DOI：
10.1136/bjo.2008.148346
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发表时间：
2009-01-01
影响因子：
4.1
通讯作者：
Rootman, D. S.
中科院分区：
文献类型：
--
作者：
Bahar, I.;Kaiserman, I.;Rootman, D. S.
目的：比较启用 IntraLase 的顶帽穿透性角膜移植术 (IEK) 的结果与手动顶帽穿透性角膜移植术 (TH-PKP) 和传统 PKP 的回顾性结果。 患者/方法：这项非随机前瞻性研究包括 94 只眼睛：23 只眼睛接受了 IEK，36 只眼睛接受了 TH-PKP，35 只眼睛接受了传统 PKP。分析术前和术后明显屈光、裸眼视力和最佳眼镜矫正视力 (BSCVA)、高阶眼像差 (HOA)、内皮细胞计数和并发症。结果：随访 12 个月时，IEK 组的平均 log MAR BSCVA 为 0.32 (SD 0.31)，TH PKP 组为 0.53 (0.36)传统 PKP 组 (p = 0.03) 和 0.39 (0.30) (p = 0.4)。各组之间的平均球镜当量相似，均小于-2.2 屈光度。 IEK 组和传统 PKP 组的平均柱镜相似（分别为 3.6 (1.9) 屈光度和 4.1 (1.8) 屈光度），并且显着低于 TH-PKP 组（5.1 (3.2) 屈光度，p = 0.04）。三组研究的并发症发生率和高阶眼像差相似。与传统 PKP 相比，IEK 和 TH-PKP 组在 12 个月的随访中平均内皮细胞损失显着降低（分别为 32.4% 和 22.3% vs 40.8%）（p = 0.05）。 IEK 组的平均拆线时间为 4.1 (1.2) 个月，TH-PKP 组的平均拆线时间为 3.9 (1.5) 个月，而传统 PKP 组的平均拆线时间为 9.7 (1.1) 个月 (p
Aim: To compare the outcomes of IntraLase-enabled top hat penetrating keratoplasty (IEK) versus retrospective results of manual top hat penetrating keratoplasty (TH-PKP) and conventional PKP.Patients/methods: This non-randomised prospective study included 94 eyes: 23 eyes underwent IEK, 36 TH-PKP and 35 conventional PKP. Preoperative and postoperative manifest refraction, uncorrected and best-spectacle corrected visual acuity (BSCVA), high-order ocular aberrations (HOA), endothelial cell counts and complications were analysed.Results: At 12 months of follow-up, the mean log MAR BSCVA was 0.32 (SD 0.31) in the IEK group, 0.53 (0.36) in the TH PKP group (p = 0.03) and 0.39 (0.30) in the conventional PKP group (p = 0.4). The mean spherical equivalent was similar between the groups and was less than -2.2 dioptres. The mean cylinder was similar in the IEK and conventional PKP group (3.6 (1.9) dioptres and 4.1 (1.8) dioptres, respectively), and was significantly lower than the TH-PKP group (5.1 (3.2) dioptres, p = 0.04). The complications rate and high-order ocular aberrations were similar between the three groups studied. The mean endothelial cell loss was significantly lower at 12 months of follow-up in the IEK and the TH-PKP groups versus conventional PKP (32.4% and 22.3% vs 40.8%, respectively) (p = 0.05). The mean time to suture removal was 4.1 (1.2) months in the IEK group and 3.9 (1.5) months in the TH-PKP group versus 9.7 (1.1) months in the conventional PKP group (p