STRUCTURE OF RIBONUCLEOPROTEIN OF INFLUENZA VIRUS
STRUCTURE OF RIBONUCLEOPROTEIN OF INFLUENZA VIRUS
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DOI：
10.1128/jvi.10.4.795-800.1972
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发表时间：
1972-01-01
影响因子：
5.4
通讯作者：
DUESBERG, PH
中科院分区：
文献类型：
--
作者：
COMPANS, RW;CONTENT, J;DUESBERG, PH
流感病毒的核糖核蛋白（RNP）的内部成分被分离成不同的大小类的甘油梯度沉降和电子显微镜检查，通过使用醋酸铀酰阳性染色。大的RNP在90至110 nm处具有长度分布的峰，中等的在60至90 nm处，小的在30至50 nm处。这些长度可以与各种RNP大小类别中所含核糖核酸的估计分子量相关。RNP结构似乎由自身折叠并以规则的双螺旋排列卷曲的链组成。
The ribonucleoprotein (RNP) internal components of influenza virus were separated into distinct size classes by sedimentation in glycerol gradients and examined by electron microscopy by using positive staining with uranyl acetate. The large RNP have a peak in length distribution at 90 to 110 nm, the medium, at 60 to 90 nm, and the small, at 30 to 50 nm. These lengths can be correlated with the estimated molecular weights of the ribonucleic acids contained in the various RNP size classes. The RNP structure appears to consist of a strand which is folded back on itself and coiled in a regular double-helical arrangement.