A dinuclear Ni(μ-H)Ru complex derived from H2
A dinuclear Ni(μ-H)Ru complex derived from H2
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DOI：
10.1126/science.1138751
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发表时间：
2007-04-27
期刊：
影响因子：
56.9
通讯作者：
Kuroki, Ryota
中科院分区：
文献类型：
--
作者：
Ogo, Seiji;Kabe, Ryota;Kuroki, Ryota
[NiFe]氢化酶活性位点的模型已被证明具有挑战性的准备。我们分离出一个顺磁性的双核镍-钌配合物与桥连配体的异裂的H-2的双核NiRu水配合物在水中在环境条件下（20摄氏度和1个大气压）。六配位Ni（μ-H）Ru配合物的结构是由中子衍射分析明确确定的，它最接近于所提出的酶活性形式的核心结构的有效类似物。
Models of the active site in [NiFe] hydrogenase enzymes have proven challenging to prepare. We isolated a paramagnetic dinuclear nickel-ruthenium complex with a bridging hydrido ligand from the heterolytic cleavage of H-2 by a dinuclear NiRu aqua complex in water under ambient conditions (20 degrees C and 1 atmosphere pressure). The structure of the hexacoordinate Ni(mu-H) Ru complex was unequivocally determined by neutron diffraction analysis, and it comes closest to an effective analog for the core structure of the proposed active form of the enzyme.