Pulmonary function testing in the rabbit.
Pulmonary function testing in the rabbit.
复制标题
兔子的肺功能测试。
DOI：
10.1152/jappl.1966.21.3.1094
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发表时间：
1966
影响因子：
3.3
通讯作者：
R. Schmidt
中科院分区：
文献类型：
--
作者：
J. Davidson;K. Wasserman;G. Lillington;R. Schmidt
约瑟夫·戴维森，格伦·卡尔曼·瓦瑟曼恩德河，利灵顿威廉·施密特。家兔肺功能试验。J. Appl. Physiol.21（s）：Iogpog8. 1966年：本文报告了家兔肺功能测定的实用性。该方法利用了为人类研究开发的技术。它涉及全身麻醉和气管插管与一个袖口管，以提供一个防漏气道。这允许每周对通气量、FRC、肺顺应性和非弹性阻力进行系列测试。此外，浅表的、容易进入的耳动脉有助于采集动脉血，用于研究未麻醉动物的气体张力。所有这些试验均耐受良好。结论是，兔是一个非常适合的主题，在哺乳动物实验生理学的功能呼吸研究。麻醉;气管内插管;食管压力;合规;肺压力-容积曲线;动脉血气;体积描记器功能残气量
DAVIDSON, JOSEPH T., KARLMAN WASSERMAN, GLEN A. LILLINGTON, END R. WILLIAM SCHMIDT. Pulmonary function testing in the rabbit. J. Appl. Physiol. 21 (s): Iogpog8. 1966.: This communication reports on the practicability of pulmonary function testing in the rabbit. The methodology made use of techniques developed for human studies. It involved general anesthesia and endotracheal intubation with a cuffed tube to provide a leakproof airway. This permitted serial testing at weekly intervals of ventilation, FRC, pulmonary compliance, and nonelastic resistance. In addition, a superficial, easily accessible ear artery facilitated the collection of arterial blood for study of gas tensions in the unanesthetized animal. All these tests were well tolerated. It is concluded that the rabbit is an eminently suitable subject for functional respiratory studies in mammalian experimental physiology. anesthesia; endotracheal intubation; esophageal pressure; compliance; lung pressure-volume curve; arterial blood gases; plethysmograph; functional residual capacity