Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals.
Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals.
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DOI：
10.1016/j.jcmgh.2016.04.003
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发表时间：
2016-07
影响因子：
7.2
通讯作者：
Linden, David R
中科院分区：
文献类型：
--
作者：
Camilleri, Michael;Linden, David R
准确评估胃肠道复杂运动功能的能力对于理解和治疗消化系统疾病具有巨大价值。与其他具有相对更多节律性和模式化运动行为的平滑肌或心肌器官系统不同，消化道的多样运动行为的复杂性使得胃肠运动功能的临床和临床前测试的开发和使用具有很大的挑战。也许正是这种复杂性，以及胃肠道功能对整体健康和福祉的重要性，吸引了早期的生理学家，并继续推动现代生理学家和临床诊断学家开发新的更准确的运动测量方法。也正是由于这种复杂性，这些措施的标准化提出了广泛采用的障碍，更复杂的运动功能的测量仍然主要限于三级转诊中心。
The ability to assess the complex motor functions of the gastrointestinal tract accurately has been of tremendous value to understanding and treating digestive diseases. Unlike other smooth or cardiac muscle organ systems with relatively more rhythmic and patterned motor behavior, the complexity of the diverse motor behaviors of the alimentary canal have made the development and use of clinical and preclinical tests of gastrointestinal motor function a great challenge. It is perhaps this complexity, as well as the importance of gastrointestinal function to overall health and well-being, that have fascinated early physiologists and continue to push modern physiologists and clinical diagnosticians to develop new and more accurate measurements of motility. It is also because of this complexity that the standardization of these measures presents hurdles to broad adoption and that the measurements of the more complex motility functions remain restricted mainly to tertiary referral centers.