Abnormal tibiofemoral kinematics following ACL reconstruction are associated with early cartilage matrix degeneration measured by MRI T1rho
Abnormal tibiofemoral kinematics following ACL reconstruction are associated with early cartilage matrix degeneration measured by MRI T1rho
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DOI：
10.1016/j.knee.2011.06.015
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发表时间：
2012-08-01
期刊：
影响因子：
1.9
通讯作者：
Li, Xiaojuan
中科院分区：
文献类型：
--
作者：
Haughom, Bryan;Schairer, William;Li, Xiaojuan
目的：ACL 重建后运动学的改变可能是创伤后骨关节炎的一个原因。 T-1 rho MRI 是一种检测早期软骨基质变性的技术。我们的研究旨在评估 ACL 重建后的运动学、软骨健康状况（使用 T-1 rho MRI），并评估 ACL 重建后的运动学改变是否与早期软骨退化相关。方法：11 名患者（平均年龄：33 +/- 9 岁）在 ACL 重建后 18 +/- 5 个月接受了 3 T MRI。图像是在模拟负载 (125 N) 下伸展和弯曲 30 度时获得的。分析了屈曲和伸展之间的胫骨旋转（TR）和胫骨前平移（ATT），以及膝关节软骨的 T-1 rho 松弛时间。软骨分为五个室：内侧和外侧股骨髁（MFC/LFC）、内侧和外侧胫骨（MT/LT）和髌骨。还对股骨承重 (wb) 区域进行了子分析。患者被分类为 ATT 和 TR 以及 T-1 rho“异常”或“恢复”，比较两组患者之间的百分比增加。 结果：作为一组，ACL 重建和对侧膝关节运动学之间没有显着差异，但存在个体差异。 MFC 和 MFC-wb 区域的 T-1 rho 弛豫时间升高 (p
Purpose: Altered kinematics following ACL-reconstruction may be a cause of post-traumatic osteoarthritis. T-1 rho MRI is a technique that detects early cartilage matrix degeneration. Our study aimed to evaluate kinematics following ACL-reconstruction, cartilage health (using T-1 rho MRI), and assess whether altered kinematics following ACL-reconstruction are associated with early cartilage degeneration.Methods: Eleven patients (average age: 33 +/- 9 years) underwent 3 T MRI 18 +/- 5 months following ACL-reconstruction. Images were obtained at extension and 30 degrees flexion under simulated loading (125 N). Tibial rotation (TR) and anterior tibial translation (ATT) between flexion and extension, and T-1 rho relaxation times of the knee cartilage were analyzed. Cartilage was divided into five compartments: medial and lateral femoral condyles (MFC/LFC), medial and lateral tibias (MT/LT), and patella. A sub-analysis of the femoral weight-bearing (wb) regions was also performed. Patients were categorized as having "abnormal" or "restored" ATT and TR, and T-1 rho, percentage increase was compared between these two groups of patients.Results: As a group, there were no significant differences between ACL-reconstructed and contralateral knee kinematics, however, there were individual variations. T-1 rho relaxation times of the MFC and MFC-wb region were elevated (p