Cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the bologna criteria
Cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the bologna criteria
复制标题
根据博洛尼亚标准，卵巢反应不佳者在三个卵巢刺激 IVF 周期后的累积活产率
DOI：
10.1007/s11596-013-1134-7
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发表时间：
2013-06-01
影响因子：
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通讯作者：
Chen, Shi-ling
中科院分区：
文献类型：
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作者：
Ke, Hui;Chen, Xin;Chen, Shi-ling
本研究探讨了根据Bologna标准对卵巢反应不良患者进行3个卵巢刺激体外受精（IVF）周期后的累积活产率。在这项回顾性队列研究中，纳入了2006年7月至2012年1月在我们的IVF中心进行的第一个卵巢刺激IVF周期中根据博洛尼亚标准的479例卵巢反应不良者。采用乐观法和悲观法计算累积活产率。根据Bologna标准，卵巢低反应者在3个卵巢刺激IVF周期后的累积活产率为12.7%-20.5%。年龄≤35岁、36-39岁和≥40岁的不良反应者的三个周期累积活产率分别为18.5%-24.5%、13.2%-27.4%和8.6%-14.9%。总之，根据Bologna标准的不良反应者在三个卵巢刺激IVF周期后可以获得可接受的累积活产率，特别是年龄<40岁的不良反应者。
This study explored the cumulative live birth rate after three ovarian stimulationin vitrofertilization (IVF) cycles for poor ovarian responders according to the Bologna criteria. In this retrospective cohort study, 479 poor ovarian responders according to the Bologna criteria in the first ovarian stimulation IVF cycle between July 2006 and January 2012 in our IVF centre were included. The cumulative live birth rate was calculated by optimistic and pessimistic methods. The cumulative live birth rate after three ovarian stimulation IVF cycles for poor ovarian responders according to the Bologna criteria was 12.7%–20.5%. The three-cycle cumulative live birth rate was 18.5%–24.5%, 13.2%–27.4% and 8.6%–14.9% for poor responders aged ≤35 years, 36–39 years and ≥40 years, respectively. In conclusion, poor responders according to the Bologna criteria can receive an acceptable cumulative live birth rate after three ovarian stimulation IVF cycles, especially poor responders aged <40 years.