HUMAN EXPOSURE TO 4.0-TESLA MAGNETIC-FIELDS IN A WHOLE-BODY SCANNER
HUMAN EXPOSURE TO 4.0-TESLA MAGNETIC-FIELDS IN A WHOLE-BODY SCANNER
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DOI：
10.1118/1.596827
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发表时间：
1992-07-01
期刊：
影响因子：
3.8
通讯作者：
MCDOUGALL, IL
中科院分区：
文献类型：
--
作者：
SCHENCK, JF;DUMOULIN, CL;MCDOUGALL, IL
详细介绍了一个大的，高度均匀的磁铁设计，允许全身磁共振成像和光谱在4 T的设计，施工，属性和性能。磁体的电感为1289 H，在额定磁场下的储能为33.4 MJ。在12个月的时间里，对11名不同程度暴露于该磁场的志愿者的健康状况进行了跟踪，没有发现与这种暴露有关的变化。一些志愿者报告说，在他们的一些接触过程中，有一种轻微的感觉体验，显然与磁场内的运动有关。一份关于磁共振扫描仪相关的感觉效应的问卷，可能是由这些仪器的静磁场引起的，给了9名在1.5 T扫描仪和4 T扫描仪内有经验的受访者，以及另一组24名仅在1.5 T扫描仪内有经验的受访者。对于眩晕、恶心和金属味的感觉，有统计学显著性（p < 0.05）证据表明场依赖效应在4 T时更大。此外，有证据表明，在静态场中眼睛的运动会引起运动诱导的磁磷现象。这些结果表明，实验性全身扫描仪在4 T下工作的实用性，以及与静磁场内运动相关的人类轻度感觉效应的可能性。结果还表明，在1.5 T至2 T及以下的常规磁共振扫描仪的静态场下，未受损患者暴露于静态场的安全裕度可能较宽。
Details are given for the design, construction, properties, and performance of a large, highly homogeneous magnet designed to permit whole-body magnetic resonance imaging and spectroscopy at 4 T. The magnet has an inductance of 1289 H and a stored energy of 33.4 MJ at rated field. The health of a group of 11 volunteers who had varying degrees of exposure to this field was followed over a 12-month period and no change that could be associated with this exposure was detected. A mild level of sensory experiences, apparently associated with motion within the field of the magnet, was reported by some of the volunteers during some of their exposures. A questionnaire regarding sensory effects associated with magnetic resonance scanners and possibly caused by the static magnetic field of these instruments, was given to nine respondents who had experience within both 1.5-T scanners and this 4-T scanner and to another group of 24 respondents who had experience only within 1.5-T scanners. For the sensations of vertigo, nausea, and metallic taste there was statistically significant (p < 0.05) evidence for a field-dependent effect that was greater at 4 T. In addition, there was evidence for motion-induced magnetophosphenes caused by motion of the eyes within the static field. These results indicate the practicality of experimental whole-body body scanners operating at 4 T and the possibility of mild sensory effects in humans associated with motion within a static magnetic field. The results also indicate the likelihood of a wide margin of safety for the exposure of noncompromised patients to the static fields of conventional magnetic resonance scanners operated at 1.5 to 2 T and below.