Paternity Balancing
Paternity Balancing
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DOI：
10.1159/000351857
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发表时间：
2013-01-01
影响因子：
2.2
通讯作者：
Britt, David W.
中科院分区：
文献类型：
--
作者：
Evans, Mark I.;Andriole, Stephanie;Britt, David W.
背景：“传统”的同性恋夫妇和现在越来越多的同性恋夫妇使用妊娠载体和卵子捐赠者。三对男同性恋夫妇都使用卵子捐赠者和携带双方精液的妊娠载体，生下了三胞胎。所有人都希望根据标准医学适应症减少双胞胎数量，但要求，如果合理可能，双胞胎的父亲是一对。方法：按照我们通常的临床方案，我们在12周时对所有胎儿进行绒毛膜绒毛取样，获得FISH和核型。为了进行父系分析，将绒毛上的14个多态性分子标记与两名男子的DNA样本进行比较，以包括或排除每个标记。结果：标准评定均正常。亲子鉴定显示，其中一方是两个三胞胎的父亲，另一方是一个。在所有病例中，其中一个“双胞胎”减少了，随后出现了良好的临床结果。结论：父权平衡增加了满足男同性恋伴侣计划生育愿望的选择。我们认为它与减少的性别偏好相当，即它可以被考虑，但只能完全服从于任何临床标准。父权平衡引发了与性别偏好减少类似的伦理问题，但可能会增加患者的自主权和主流对稳定同性恋家庭的接受度。巴塞尔S. Karger股份有限公司版权所有
Background: Gestational carriers and egg donors have been used by 'traditional' and now increasingly, gay couples. Three gay male couples, all using egg donors and gestational carriers with semen from both partners, had triplets. All desired reductions to twins for the standard medical indications, but requested, if reasonably possible, to have twins with one fathered by each partner. Methods: Following our usual clinical protocol, we performed chorionic villus sampling at 12 weeks on all fetuses obtaining FISH and karyotype. For paternity analysis, 14 polymorphic molecular markers on villi were compared to DNA samples from the two men to include or exclude each. Results: Standard assessments were all normal. Paternity testing showed that one partner fathered two of the triplets, and the other one. In all cases, one of the 'twins' was reduced with good clinical outcomes ensuing. Conclusions: Paternity balancing increases options for satisfying family planning desires of gay male couples. We believe it comparable to gender preferences in reductions, i.e. it can be considered but only completely subservient to any clinical criteria. Paternity balancing raises similar ethical issues as reduction with gender preferences, but may increase patient autonomy and mainstream acceptance of stable, gay families. Copyright (C) 2013 S. Karger AG, Basel