Diffuse white-matter disease in the geriatric population. A clinical, neuropathological, and CT study.
Diffuse white-matter disease in the geriatric population. A clinical, neuropathological, and CT study.
复制标题
老年人群中的弥漫性白质疾病。
作者：
K. Goto;N. Ishii;H. Fukasawa
本文报道6例皮质下动脉硬化性脑病（SAE）尸检的CT表现。双脑半球深部白质弥漫性密度不均匀降低，侧脑室中度扩张，边缘粗糙。尸检时最典型的病理表现是弥漫性不完全梗死，包含多个小梗死，以及囊肿形成和髓动脉明显的狭窄性动脉粥样硬化改变。临床特征包括斑块性精神缺失、额叶综合征、轻微运动体征和高血压。作者认为SAE或类似的疾病可能发生在大多数多发性梗死性痴呆病例中。
CT findings in 6 autopsy cases of subcortical arteriosclerotic encephalopathy (SAE) are reported. A diffuse area of nonhomogeneous decreased density was observed in the deep white matter of both cerebral hemispheres, together with moderate dilatation of the lateral ventricles and ragged margins. The most characteristic pathological findings at autopsy were a diffuse area of incomplete infarction containing multiple small infarcts as well as cyst formation and marked stenotic atherosclerotic changes in the medullary arteries. Clinical features included patchy mental lapses, frontal-lobe syndromes, minor motor signs, and hypertension. The authors feel that SAE or a similar disease might occur in most cases of multi-infarct dementia.