Single photon emission CT perfusion imaging of cerebral blood flow of early syphilis patients.
Single photon emission CT perfusion imaging of cerebral blood flow of early syphilis patients.
复制标题
早期梅毒患者脑血流的单光子发射CT灌注成像
作者：
Xin Shi;Jinchang Wu;Zeng;Jun Tang;Yuhua Su
目的
目的探讨早期梅毒患者的脑血流量。
方法
应用~（99）Tc（m）-ECD脑灌注显像剂，对32例早期梅毒患者和15例正常人进行单光子发射计算机断层显像（SPECT）。对每个BSPECT图像进行视觉分析。
结果
32例早期梅毒患者脑血流灌注普遍呈斑片状低灌注。32例患者中有14例出现了48次明显的局部脑血流灌注不足。低灌注区呈斑片状分布，涉及左额叶（6次发作）、右额叶（3次发作）、左顶叶（7次发作）、右顶叶（6次发作）、左颞叶（11次发作）、右颞叶（5次发作）、左枕叶（3次发作）、左基底节（3次发作）、小脑（1次发作）和神经核（1次发作）。对照组未见异常。
结论
早期梅毒患者存在脑血流异常。SPECT显像上普遍的斑片状低灌注是常见的。
OBJECTIVE
To injvestigate the cerebral blood flow of patients with early syphilis.
METHODS
(99)Tc(m)-ECD as brain perfusion imaging agent was used in single photon emission computed tomography (SPECT) for 32 patients with early syphilis and 15 controls. Visual analyses were made on every BSPECT image.
RESULTS
The 32 patients with early syphilis had general, patchy hypoperfusion of cerebral blood flow. Fourteen of the 32 patients had 48 episodes of marked patchy hypoperfusion of rCBF. The responsible areas of hypoperfusion in a patchy distribution involved the left frontal lobe (6 episodes), right frontal lobe (3), left parietal lobe (7), right parietal lobe (6), left temporal lobe (11), right temporal lobe (5), left occipital lobe (3), left basal ganglia (3), cerebellum (1), and nerve nuceus (1). No abnormality was found in the control group.
CONCLUSIONS
Cerebral blood flow abnormalities exist in patients with early syphilis. General patchy hypoperfusion on SPECT imaging is common.