BI-RADS for sonography: Positive and negative predictive values of sonographic features

BI-RADS for sonography: Positive and negative predictive values of sonographic features
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DOI:
10.2214/ajr.184.4.01841260
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发表时间:
2005-04-01
影响因子:
5
通讯作者:
Baker, JA
Baker, JA
中科院分区:
医学2区
文献类型:
--
作者:
Hong, AS;Rosen, EL;Baker, JA

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OBJECTIVE.本研究的目的是评估的阳性预测值(PPV)和阴性预测值(NPV)的新的超声BI-RADS词典中描述的功能,用于评估与已知的组织学诊断的实性肿块。由三位专门的乳腺放射科医生之一分析了403个实体病变的超声图像。使用超声BI-RADS词典中的特征描述每个病变。病变描述和活检结果相关。计算PPV和NPV。病理结果显示恶性肿瘤141例(35%)。超声BI-RADS对恶性肿瘤有较高预测价值的指标包括边缘毛刺(86%,19/22)、形态不规则(62%,102/164)和方向不平行(69%,75/109)。超声BI-RADS对良性病变的预测率较高的指标包括边界清楚(90%,160/178)、平行方向(78%,228/294)和椭圆形(84%,200/237)。对于肿块边缘、形状、方向、病灶边界、回声模式和后方声学特征的超声BI-RADS特征,恶性和良性肿块的描述符有显著差异(p < 0.001)。新的超声BI-RADS词汇表中的描述词可用于区分良性和恶性实性肿块。
OBJECTIVE. The purpose of this study was to assess the positive predictive value (PPV) and negative predictive value (NPV) of features described in the new sonographic BI-RADS lexicon for evaluating solid masses with known histologic diagnoses.MATERIALS AND METHODS. Sonograms of 403 solid lesions were analyzed by one of three dedicated breast radiologists. Each lesion was described using features from the sonographic BI-RADS lexicon. Lesion description and biopsy results were correlated. PPV and NPV were calculated.RESULTS. Histologic results showed that 141 (35%) of 403 masses were malignant. Sonographic BI-RADS descriptors showing high predictive value for malignancy include spiculated margin (86%,19/22), irregular shape (62%,102/164), and nonparallel orientation (69%,75/109). Sonographic BI-RADS descriptors highly predictive of benign lesions include circumscribed margin (90%,160/178), parallel orientation (78%, 228/294), and oval shape (84%,200/237). For the sonographic BI-RADS features of mass margin, shape, orientation, lesion boundary, echo pattern, and posterior acoustic features, descriptors chosen were significantly (p < 0.001) different for malignant and benign masses.CONCLUSION. Descriptors from the new sonographic BI-RADS lexicon can be useful in differentiating benign from malignant solid masses.