Quality of Life of Patients With Bilateral Vestibulopathy
Quality of Life of Patients With Bilateral Vestibulopathy
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DOI：
10.1177/000348941212100708
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发表时间：
2012-07-01
影响因子：
1.4
通讯作者：
Kingma, Herman
中科院分区：
文献类型：
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作者：
Guinand, Nils;Boselie, Frans;Kingma, Herman
目的：目前尚无证据表明双侧前庭病变(BV)的有效治疗方法。他们的主要抱怨是视觉震荡和不平衡。关于BV对他们的生活质量的影响的观点是有争议的，而且他们的障碍并不总是被认识到，甚至在耳神经科医生中也是如此。本研究的目的是客观地评估BV患者的健康状况，以评估是否需要继续努力开发新的治疗方法。方法：对39例BV患者进行简明健康调查(SF-36)、头晕残疾问卷(DHI)、短时跌倒疗效量表(Short Fes-I)和视振荡严重程度问卷调查。SF-36的得分与普通荷兰人的得分进行了比较。DHI评分与视震荡严重程度评分相关。将短的FES-I评分与老年人群的评分进行比较。结果：与普通荷兰人相比，BV患者在“身体功能”、“身体角色”、“一般健康”、“活力”和“社会功能”SF-36变量上得分显著降低(p<；0.05)。DHI评分与视震荡严重程度评分呈显著正相关(r=0.75p<；0.000001)。短的FES-I评分表明患者对跌倒的恐惧有轻微到中度的增加。残留耳石功能的BV患者与完全BV患者之间的评分差异无统计学意义。听力状况与SF-36评分无相关性。结论：这一结果与我们的临床印象相关，即BV对身体和社会功能有强烈的负面影响，导致生活质量下降。显然需要一种治疗方案。开发CIF前庭植入物的努力是合理的。
Objectives: Currently, there is no evidence of an effective treatment for patients with bilateral vestibulopathy (BV). Their main complaints are oscillopsia and imbalance. Opinions about the impact of BV on their quality of life are controversial, and their handicap is not always recognized, even among otoneurologists. The aim of this study was to objectively assess the health status of BV patients in order to evaluate the need for pursuing efforts toward the development of new treatments.Methods: The Short-Form Health Survey (SF-36), the Dizziness Handicap Inventory (DHI), the Short Falls Efficacy Scale International (Short FES-I), and an oscillopsia severity questionnaire were submitted to 39 BV patients. The SF-36 scores were compared to the scores of a general Dutch population. The DHI scores were correlated to the oscillopsia severity scores. The Short FES-I scores were compared to scores in an elderly population. Residual otolithic function was correlated to all scores, and hearing to SF-36 scores.Results: Compared to the general Dutch population, the BV patients scored significantly worse on the "physical functioning," "role physical," "general health," "vitality," and "social functioning" SF-36 variables (p < 0.05). The DHI scores were strongly correlated with the oscillopsia severity scores (r = 0.75; p < 0.000001). The Short FES-I scores indicated a slight to moderate increase in the patients' fear of falling. No significant score differences were found between BV patients with residual otolithic function and patients with complete BV. There was no correlation between hearing status and SF-36 scores.Conclusions: The results correlate with our clinical impression that BV has a strong negative impact on physical and social functioning, leading to a quality-of-life deterioration. There is a clear need for a therapeutic solution. Efforts toward the development cif a vestibular implant are justified.