The evolution of insect germline specification strategies.
The evolution of insect germline specification strategies.
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DOI：
10.1016/j.cois.2016.02.013
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发表时间：
2016-02
影响因子：
5.3
通讯作者：
Lynch JA
中科院分区：
文献类型：
--
作者：
Quan H;Lynch JA
生殖系的建立对于有性生殖的生物体是必不可少的。在动物中，有两种主要的策略来指定生殖系：母体提供和合子诱导。母系提供模式的分子基础已经在几种模式生物（苍蝇、青蛙、鱼和线虫）中得到了很好的表征，而合子诱导模式的分子基础主要在哺乳动物模型（如小鼠）中进行了研究。生殖系决定模式的转变出乎意料地频繁发生，许多这样的转变在昆虫中发生了几次。鉴于其一般的温顺性和快速增长的基因组和遗传工具适用于许多物种，昆虫提出了一个独特的强大的模型系统，了解生殖策略的重大转变，一般的发育过程。
The establishment of the germline is essential for sexually reproducing organisms. In animals, there are two major strategies to specify the germline: maternal provision and zygotic induction. The molecular basis of the maternal provision mode has been well characterized in several model organisms (fly, frog, fish, and nematode), while that of the zygotic induction mode has mainly been studied in mammalian models such as the mouse. Shifts in germline determination modes occur unexpectedly frequently and many such shifts have occurred several times among insects. Given their general tractability and rapidly increasing genomic and genetic tools applicable to many species, the insects present a uniquely powerful model system for understanding major transitions in reproductive strategies, and developmental processes in general.