Epidemiological features of Helicobacter pylori infection in developing countries
Epidemiological features of Helicobacter pylori infection in developing countries
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DOI：
10.1086/516067
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发表时间：
1997-11-01
影响因子：
11.8
通讯作者：
Bardhan, PK
中科院分区：
文献类型：
--
作者：
Bardhan, PK
幽门螺杆菌感染具有世界性分布，在发展中国家具有明显的流行病学特征。与发达国家相比，发展中国家的幽门螺杆菌感染似乎几乎普遍存在，从儿童早期就开始感染。儿童在生命的最初几个月内被感染；在一些社区，多达 50% 的儿童在 5 岁时被感染，高达 90% 的儿童在成年时被感染。在一些工业化、社会经济条件和卫生条件有所改善的发展中国家，感染率较低。间接测定的幽门螺杆菌感染率也表明其感染率比发达国家高出几倍。在不同民族和种族群体之间观察到幽门螺杆菌血清流行率存在显着差异。尽管幽门螺杆菌的传播方式仍不确定，但有证据表明存在人际传播。
Helicobacter pylori infection has a worldwide distribution, and it has distinct epidemiological features in developing countries. In contrast to that in developed countries, H. pylori infection in developing countries seems to be nearly universal, beginning in early childhood. Children become infected in the first few months of life; in some communities as many as 50% of the children are infected by the age of 5 years, and up to 90% are infected by the time they reach adulthood. In some developing countries with improvements in industrialization, socioeconomic conditions, and hygiene, infection rates are lower. The incidence of H. pylori infection, determined indirectly, also suggests a rate several times higher than that in developed countries. Marked differences in H. pylori seroprevalence have been observed between various ethnic and racial groups. Although the mode of transmission of H. pylori remains uncertain, evidence suggests person-to-person transmission occurs.