Phenytoin: plasma levels and behavioral changes associated with suppression of auditory evoked potentials in the cat.
Phenytoin: plasma levels and behavioral changes associated with suppression of auditory evoked potentials in the cat.
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苯妥英:与抑制猫听觉诱发电位相关的血浆水平和行为变化。
DOI:
10.1016/0028-3908(81)90175-1
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发表时间:
1981
影响因子:
4.7
通讯作者:
StittsworthJr,JD
中科院分区:
文献类型:
--
作者:
Faingold,CL;StittsworthJr,JD
Phenytoin (PHT) administration caused near total or total suppression of auditory evoked field potentials and brainstem auditory evoked potentials at mean plasma levels of 28.1–30.5 μg/ml. The suppression lasted for a mean of 53.5 hr and was accompanied by ataxia and other signs of PHT toxicity. Visual evoked field potentials were not consistently affected. This action may be mediated by effects on peripheral auditory receptor mechanisms.