Clinical Performance of CAD/CAM All-Ceramic Tooth-Supported Fixed Dental Prostheses: A Systematic Review and Meta-Analysis.
Clinical Performance of CAD/CAM All-Ceramic Tooth-Supported Fixed Dental Prostheses: A Systematic Review and Meta-Analysis.
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DOI：
10.3390/ma14102672
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发表时间：
2021-05-20
期刊：
影响因子：
--
通讯作者：
Patzelt SBM
中科院分区：
文献类型：
--
作者：
Saravi B;Vollmer A;Hartmann M;Lang G;Kohal RJ;Boeker M;Patzelt SBM
虽然CAD/CAM陶瓷是金属-陶瓷固定修复体的一种很有前途的替代品，但其中长期临床表现尚不清楚。本系统综述旨在评估CAD/CAM牙支撑氧化锆和二硅酸锂固定义齿（fdp）的存活率和成功率，并描述潜在的并发症特征。我们系统地检索MEDLINE和Web of Science，找到相关的前瞻性研究，随访至少一年。通过将收集到的数据与泊松回归模型相结合，我们估计了1年、5年和10年的生存率和成功率。采用描述性统计来评估纳入研究的失败和并发症的分布。纳入研究的偏倚风险用单臂试验的适应性检查表进行评估。合并估计1年、5年和10年生存率分别为93.80% ~ 94.66%、89.67% ~ 91.1%和79.33% ~ 82.20%。相应的成功率为94.53% ~ 96.77%,90.89% ~ 94.62%,81.78% ~ 89.25%。继发性龋齿是最常见的失败原因，其次是贴面脱落。除失败外，最常见的并发症原因是贴面脱落，但需要干预。纳入研究的偏倚风险总体上是可以接受的，其中7项研究为低偏倚风险，8项研究为中等偏倚风险，3项研究为严重偏倚风险。目前对CAD/ cam支持的fdp的荟萃分析显示，在长达10年的暴露中，生存率和成功率令人满意。需要更多关注长期表现的前瞻性研究来加强文献中现有的证据。
Although CAD/CAM ceramics present a promising alternative to metal-ceramic fixed dental prostheses, little is known about their mid- and long-term clinical performance. This systematic review aims to estimate the survival and success rates and describes the underlying complication characteristics for CAD/CAM tooth-supported zirconia- and lithium disilicate-based fixed dental prostheses (FDPs). We systematically searched MEDLINE and Web of Science to find relevant prospective studies with a follow-up of at least one year. We estimated pooled 1-, 5-, and 10-year survival and success rates by combining the collected data in a Poisson regression model. Descriptive statistics were conducted to evaluate the distribution of failures and complications in the included studies. Risk of bias for the included studies was assessed with an adapted checklist for single-arm trials. Pooled estimated 1-, 5-, and 10-year survival rates ranged from 93.80% to 94.66%, 89.67% to 91.1%, and 79.33% to 82.20%, respectively. The corresponding success rates excluding failures, but including any other types of intervention were 94.53% to 96.77%, 90.89% to 94.62%, and 81.78% to 89.25%. Secondary caries was the most frequent cause of failure, followed by chipping of the veneering. The most common cause of complication excluding failures but requiring intervention was chipping of the veneering. Risk of bias was generally acceptable for the included studies, with seven studies associated with low risk of bias, eight studies with a moderate risk of bias, and three studies with serious risk of bias. The current meta-analysis on CAD/CAM-supported FDPs revealed satisfying survival and success rates for up to 10 years of exposure. More prospective studies focusing on long-term performance are needed to strengthen the evidence currently available in the literature.
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影响因子：
4.6
作者：
Goodacre, Brian J.;Goodacre, Charles J.;Kattadiyil, Mathew T.
通讯作者：
Kattadiyil, Mathew T.
影响因子：
4.6
作者：
Malament, Kenneth A.;Natto, Zuhair S.;Weber, Hans-Peter
通讯作者：
Weber, Hans-Peter
影响因子：
2.9
作者：
Cattoni, Francesca;Tete, Giulia;Cappare, Paolo
通讯作者：
Cappare, Paolo
影响因子：
4.4
作者：
Burke, F. J. T.;Crisp, R. J.;Tulloch, N.
通讯作者：
Tulloch, N.
影响因子：
4.4
作者：
Ioannidis, Alexis;Bindl, Andreas
通讯作者：
Bindl, Andreas