Possibility of Odontoblasts Activity Up-Regulation due to Orthodontic Mechanical Stress in Mice
Possibility of Odontoblasts Activity Up-Regulation due to Orthodontic Mechanical Stress in Mice
复制标题
DOI：
10.2485/jhtb.19.13
复制
发表时间：
2010-04-01
影响因子：
0.4
通讯作者：
Kawakami, Toshiyuki
中科院分区：
文献类型：
--
作者：
Nakano, Keisuke;Muraoka, Rina;Kawakami, Toshiyuki
本研究采用Waldo’s法检测了小鼠实验性正畸机械应力作用后牙髓细胞，特别是成牙本质细胞中Runx 2和碱性磷酸酶（ALP）的免疫组化表达。实验结果表明，部分牙髓细胞，特别是成牙本质细胞在应激后较短时间内表达Runx 2和ALP。结果提示，应激可引起成牙本质细胞活性上调。
Using Waldo's method in mice, we examined the immunohistochemical expression of Runx2 and alkaline phosphatase (ALP) appearing in dental pulp cells, especially in odontoblasts, just after receiving experimental orthodontic mechanical stress, using Waldo's method in mice. The examination results demonstrated that some dental root pulp cells, especially some odontoblasts, expressed the Runx2 and ALP in a comparatively short time after receiving the stress. The results suggest that the stress may cause odontoblast activity up-regulation.