VIBRIO-VULNIFICUS SEPTICEMIA IN KOREA - CLINICAL AND EPIDEMIOLOGIC FINDINGS IN 70 PATIENTS
VIBRIO-VULNIFICUS SEPTICEMIA IN KOREA - CLINICAL AND EPIDEMIOLOGIC FINDINGS IN 70 PATIENTS
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DOI：
10.1016/0190-9622(91)70059-b
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发表时间：
1991-03-01
影响因子：
13.8
通讯作者：
JOH, NJ
中科院分区：
文献类型：
--
作者：
PARK, SD;SHON, HS;JOH, NJ
本文对70例创伤弧菌相关性败血症的临床特点和流行病学进行了研究。 所有患者均来自韩国西部和南部沿海地区。 大多数病例（96%）发生在夏季，男性（96%）和40岁或以上的人（90%）。 46名患者（66%）的疾病始于败血症，通常在食用生海鲜后2天内。 47例患者（67%）既存肝病，49例（70%）有酗酒史。 70例患者中，45例（79%）死亡。 64例患者（91%）入院时出现的皮肤病变中，51例出现在腿部。 从65名受试患者的血液和55名受试患者中的51名患者的皮肤病变中分离出创伤静脉。 根据病变的临床分期，组织病理学结果不同。 由于创伤弧菌败血症是一种高度致命的疾病，患有肝病或酗酒的人应避免食用或处理生海鲜。
We studied the clinical characteristics and the epidemiology of primary septicemia associated with Vibrio vulnificus in 70 patients. All patients came from the western and southern coastal areas of Korea. Most cases (96%) occurred during the summer months, in men (96%), and in persons 40 or more years of age (90%). The illness in 46 patients (66%) began with septicemia, often within 2 days of the consumption of raw seafood. Forty-seven patients (67%) had preexisting hepatic disease, and 49 (70%) had a history of alcoholism. Of the 70 patients, 45 (79%) died. The cutaneous lesions that were present on admission in 64 patients (91%) appeared on the legs in 51 of the cases. V. vulnificus was isolated from the blood of 65 patients tested and from the skin lesions of 51 of 55 patients tested. The histopathologic findings differed according to the clinical stage of lesions. Because V. vulnificus septicemia is a highly fatal disease, persons with liver disease or alcoholism should avoid eating or handling raw seafood.