Burden of stroke in black populations in sub-Saharan Africa
Burden of stroke in black populations in sub-Saharan Africa
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DOI：
10.1016/s1474-4422(07)70002-9
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发表时间：
2007-03-01
期刊：
影响因子：
48
通讯作者：
Warlow, Charles P.
中科院分区：
文献类型：
--
作者：
Connor, Myles D.;Walker, Richard;Warlow, Charles P.
撒哈拉以南非洲正在经历流行病学转型。中风和其他血管疾病日益加重了疾病负担。没有关于脑卒中死亡率、患病率、发病率和病死率的系统综述。我们对已发表的研究进行了彻底的搜索和批判性的评估。与高收入地区相比，撒哈拉以南非洲的中风死亡率与高收入国家一样高，甚至更高，并且随着年龄的增长而增加，但中风死亡的绝对数字仍然很低。目前还没有足够的以社区为基础的卒中发病率研究。以医院为基础的发病率低于高收入地区，但在年轻人中较高，可能是由于住院偏见。没有以社区为基础的病死率数据，但以医院为基础的病死率高于其他地方。中风的发病率低于高收入地区，但致残性中风同样普遍。随着该地区经济的发展，除非实施干预措施，否则中风和其他血管疾病的发病率将会增加。只有以社区为基础的发病率研究才能准确地揭示中风的负担。
Sub-Saharan Africa is undergoing epidemiological transition. Stroke and other vascular diseases increasingly contribute to the burden of disease. There are no systematic reviews of stroke mortality, prevalence, incidence, and case fatality. We combined a thorough search and critical assessment of the published research. Stroke mortality is as high, perhaps higher, than in high-income regions and increases with age in sub-Saharan Africa as in high-income countries, but the absolute number of stroke deaths remains low. There are no adequate community-based stroke incidence studies. Hospital-based incidence is lower than in high-income regions, but higher in young people, possibly due to hospital admission bias. There are no community-based data on case fatality, but hospital-based case fatality is higher than elsewhere. The prevalence of stroke is lower than in high-income regions, but disabling stroke is as prevalent. As the region develops economically, the incidence of stroke and other vascular diseases will increase unless interventions are implemented. Only community-based incidence studies will accurately reveal the burden of stroke.