Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value
Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value
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DOI：
10.1590/s1807-59322010000800002
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发表时间：
2010-06-01
期刊：
影响因子：
2.7
通讯作者：
Leone, Claudio
中科院分区：
文献类型：
--
作者：
Aprile, Marisa Matta;Feferbaum, Rubens;Leone, Claudio
目的：了解极低出生体重儿在住院期间接受母乳喂养时的生长发育和临床演变。方法：选择40例极低出生体重儿，其中10例采用母乳喂养(GI组)，30例(GII组)采用母乳喂养(GT；700卡/L，蛋白质2g/dL)。结果：GI组和GII组分别在6.3d和10.8d内达到完全肠道日粮，GI组和GII组分别在7.3周和7.8周达到2 kg体重。GI组3/10(33.3%)和GII组7/30(23.3%)发生脓毒症。坏死性小肠结肠炎在GI组中未发生，在GII组中为3/30(10.0%)。GII组尿钙4 mg/L 1例(10.0%)，尿磷1 mg/L 10例(100%)，尿钙/铬比值0.6/10例(10.0%)，尿P-u<1 mg/L 19例(63.3%)。在生长方面，GI的第50个百分位数是体重增加12.1g/天(GI)比15.8g/天(GII)，身长增加0.75厘米/周(GI)比1.02厘米/周(GII)，头围增加0.74厘米/周(GI)比0.76厘米/周(GII)。结论：母乳银行允许极低出生体重儿获得满意的生长和良好的临床演变。
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value.METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 (GII) were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters.RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (P-u) < 1 mg/L in 10/10 (100%), and Ca/Cr > 0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and P-u was < 1 mg/L in 19/30 (63.3%). In terms of growth the 50(th) percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII).CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.