Industrial Melanism in British Peppered Moths Has a Singular and Recent Mutational Origin
Industrial Melanism in British Peppered Moths Has a Singular and Recent Mutational Origin
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DOI：
10.1126/science.1203043
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发表时间：
2011-05-20
期刊：
影响因子：
56.9
通讯作者：
Saccheri, Ilik J.
中科院分区：
文献类型：
--
作者：
van't Hof, Arjen E.;Edmonds, Nicola;Saccheri, Ilik J.
在19世纪的英国，一种新的黑色胡椒蛾（被称为炭黑）的快速传播是一个教科书式的例子，说明了环境的改变如何通过基因变化产生形态适应。然而，野生型（浅色）和carbonaria形式之间差异的潜在遗传基础仍然未知。我们在家蚕17号染色体的200千碱基上对炭黑形态进行了遗传定位，发现只有一个核心序列变异与炭黑形态相关，带有近期强选择的特征。carbonaria区域与其他鳞翅目系统中主要的翅膀图案位点一致，表明该区域存在基本的颜色图案调节因子。
The rapid spread of a novel black form (known as carbonaria) of the peppered moth Biston betularia in 19th-century Britain is a textbook example of how an altered environment may produce morphological adaptation through genetic change. However, the underlying genetic basis of the difference between the wild-type (light-colored) and carbonaria forms has remained unknown. We have genetically mapped the carbonaria morph to a 200-kilobase region orthologous to a segment of silkworm chromosome 17 and show that there is only one core sequence variant associated with the carbonaria morph, carrying a signature of recent strong selection. The carbonaria region coincides with major wing-patterning loci in other lepidopteran systems, suggesting the existence of basal color-patterning regulators in this region.