THE ROLE OF PREGNANCY IN THE COURSE AND ETIOLOGY OF RHEUMATOID-ARTHRITIS
THE ROLE OF PREGNANCY IN THE COURSE AND ETIOLOGY OF RHEUMATOID-ARTHRITIS
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DOI：
10.1007/bf02207955
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发表时间：
1992-06-01
影响因子：
3.4
通讯作者：
SPECTOR, TD
中科院分区：
文献类型：
--
作者：
DASILVA, JAP;SPECTOR, TD
类风湿性关节炎（RA）的病因尚不清楚，但女性通常被认为是最重要的独立风险因素，女性发病率是男性的2至3倍。妊娠对类风湿性关节炎的巨大影响已有50多年的记录。本文综述了证据和可能的机制，怀孕修改疾病的过程中，可能会改变易感性的发展RA在以后的生活。
The aetiology of rheumatoid arthritis (RA) is unknown, although being female is generally recognized as the most important independent risk factor, the disease being 2 to 3 times more frequent in females than in males. The dramatic effect of pregnancy in rheumatoid arthritis has been documented for over 50 years. This review examines the evidence and possible mechanisms by which pregnancy modifies the disease process and may alter predisposition to the development of RA in later life.