Self-antigens and rejection: a proteomic analysis.
Self-antigens and rejection: a proteomic analysis.
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自身抗原和排斥：蛋白质组分析。
DOI：
10.1097/mot.0000000000000328
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发表时间：
2016
影响因子：
2.2
通讯作者：
Sarwal,MinnieM
中科院分区：
文献类型：
--
作者：
Yang,JoshuaYoungCynming;Sigdel,TaraK;Sarwal,MinnieM
抗体在移植肾的存活和功能障碍中起关键作用。尽管在过去的几十年里，HLA抗体已经得到了科学界的大部分关注，但针对自身抗原和非HLA来源的抗体正在获得关注。最近的出版物已经确定了与急性和慢性排斥反应相关的新的自身抗原，这增加了我们对免疫相关移植排斥反应的新参与者的理解。
Antibodies play a critical role in survival and dysfunction of a transplanted kidney. Even though HLA antibodies have been given the majority of the scientific community's attention for the past few decades, antibodies against autoantigens and that of non-HLA origin are gaining attention. Recent publications have identified novel self-antigens that are associated with acute and chronic rejection that have added to our understanding of new players in immune-related transplant rejection.