Acute Philadelphia chromosome-positive leukemia in an adolescent boy after liver transplantation.
Acute Philadelphia chromosome-positive leukemia in an adolescent boy after liver transplantation.
复制标题
一名青春期男孩肝移植后患急性费城染色体阳性白血病。
DOI：
10.1097/00043426-200307000-00014
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
McGavran,Loris
中科院分区：
文献类型：
--
作者：
Silliman,ChristopherC;Tyson,RWeslie;Wei,Qi;Karrer,FrederickG;Davies,StellaM;Blake,Marilyn;McGavran,Loris
Acute leukemia is an untoward event following immunosuppression for solid organ transplantation and is related to the oncogenic effects of Epstein-Barr viral infections. The authors report a case of acute, Philadelphia chromosome–positive, T-cell lymphoblastic leukemia following liver transplantation. Molecular typing demonstrated a minor bcr-abl rearrangement (190 kD), which persisted in remission in 71% of peripheral neutrophils as determined by fluorescence in situ hybridization. The authors conclude that this patient may have presented in a lymphoid blast crisis of chronic myelogenous leukemia with an acute T-cell leukemia/lymphoma syndrome.
