Inherited Variants in the Transferrins and Conalbumins of the Chicken

Inherited Variants in the Transferrins and Conalbumins of the Chicken
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鸡转铁蛋白和伴清蛋白的遗传变异

DOI:
10.1038/1951026b0
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发表时间:
1962
期刊:
影响因子:
64.8
通讯作者:
E. M. McDERMID
E. M. McDERMID
中科院分区:
综合性期刊1区
文献类型:
--
作者:
A. Ogden;J. Morton;D. Gilmour;E. M. McDERMID

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之前对鸡血清蛋白的电泳研究采用了移动边界 1-5、纸张 6,7 或淀粉凝胶 8,9 技术,后者使用“连续”硼酸盐缓冲液。据报道,个体血清之间的差异不同程度地取决于性别1,2,6,成熟和产卵的开始时间4,7,8,性激素治疗4,6,或胚胎发育阶段3,5,7,9;但没有发现遗传差异。在 Poulik10 不连续缓冲系统中使用水平淀粉凝胶电泳,Lush11 和我们自己都获得了显着提高的区域分辨率。前者11证实并扩展了先前关于性别和产蛋导致的变异的知识,但没有在66只不同品种鸡的血清中发现遗传变异。我们在几个研究中的一个品种中发现了遗传变异,并且还发现了蛋清蛋白的平行遗传变异。
PREVIOUS electrophoretic studies of the serum proteins of the chicken have utilized moving boundary1–5, paper6,7, or starch-gel8,9techniques, the latter with ‘continuous’ borate buffer. Differences between individual sera were reported dependent variously on sex1,2,6, onset of maturity and egg-laying4,7,8, treatment with sex hormones4,6, or stage of embryonic development3,5,7,9; but no inherited differences were found. Using horizontal starch-gel olectrophoresis in the Poulik10discontinuous buffer system, both Lush11and ourselves have obtained considerably improved resolution of the zones. The former11confirmed and extended previous knowledge of variation dependent on sex and egg-laying, but did not find inherited variation among the sera of 66 chickens of various breeds. We have found inherited variation on one breed out of several studied, and have also found parallel inherited variation in egg-white protein.