CHARACTERISTICS OF NEURONS IN AUDITORY-CORTEX OF MONKEYS PERFORMING A SIMPLE AUDITORY TASK
CHARACTERISTICS OF NEURONS IN AUDITORY-CORTEX OF MONKEYS PERFORMING A SIMPLE AUDITORY TASK
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DOI：
10.1152/jn.1981.45.1.16
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发表时间：
1981-01-01
影响因子：
2.5
通讯作者：
OCONNOR, TA
中科院分区：
文献类型：
--
作者：
PFINGST, BE;OCONNOR, TA
研究人员在未麻醉的猴子中研究了听觉皮层 A1 区和周围带区的 241 个神经元的反应特征，这些猴子正在执行简单的听觉反应时间任务。最佳频率、时间响应模式和其他响应特性的估计是在线进行的。 154 个单元的数据记录在磁带上，用于离线定量分析。在 A1 和 L 区可以看到清晰的音调组织，高频代表后面，低频代表前面。该组织比麻醉猴子皮层中所见的组织更为复杂。简单的主题组织也有明显的例外。在所研究的细胞中，22% 显示单调速率与强度函数，53% 显示简单非单调函数，25% 显示复杂非单调函数。这种强度信息的表示与类似情况下报告的下丘的表示明显不同。在皮质水平上，非单调强度函数的数量显着增加，表明皮质可能参与需要有关刺激强度的特定信息的过程。最常见的反应模式是单一的兴奋反应。响应持续时间差异很大，但大多数响应持续时间较短（大于 20 毫秒但小于 80 毫秒）。反应模式的分布与麻醉猫不同，与清醒但未经训练的猴子也略有不同。 A1 和 L 区域的响应延迟平均为 26.5 毫秒，两个区域之间没有显着差异。 RL 区域记录了许多较长延迟的响应。在可比条件下，自发率与下丘中观察到的自发率没有明显差异，但低于听觉通路外围的自发率。
Response characteristics of 241 neurons from area A1 and the surrounding belt areas of auditory cortex were studied in unanesthetized monkeys that were performing a simple auditory reaction-time task. Estimates of best frequency, temporal response pattern, and other response characteristics were made on-line. Data from 154 of the units were recorded on magnetic tape for offline quantitative analysis. A clear tonotopic organization was seen in areas A1 and L, with high frequencies represented posteriorly and low frequencies, anteriorly. The organization was more complex than that seen in anesthetized monkey cortex; there were clear exceptions to a simple tonotopic organization. Of the cells studied 22% showed monotonic rate versus intensity functions, 53% showed simple nonmonotonic functions and 25% showed complex nonmonotonic functions. This representation of intensity information is distinctly different from that reported for inferior colliculus under similar circumstances. At the cortical level, the number of nonmonotonic intensity functions is significantly increased, suggesting that the cortex may be involved in processes requiring specific information about stimulus intensity. The most common response pattern was a single on-excitatory response. Response duration varied widely, but the majority of responses were of short duration (greater than 20 ms but less than 80 ms). The distribution of response patterns differed from that in anesthetized cat and differed slightly from that in awake but untrained monkeys. Response latencies for areas A1 and L average 26.5 ms, and no significant difference was seen between the 2 areas. A number of longer latency responses were recorded from area RL. Spontaneous rate did not differ appreciably from that seen in inferior colliculus under comparable conditions, but was lower than that seen at the periphery of the auditory pathway.