Lymphocyte subset counts during the course of community-acquired pneumonia: Evolution according to age, human immunodeficiency virus status, and etiologic microorganisms
Lymphocyte subset counts during the course of community-acquired pneumonia: Evolution according to age, human immunodeficiency virus status, and etiologic microorganisms
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DOI：
10.1093/clinids/22.6.1096
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发表时间：
1996-06-01
影响因子：
11.8
通讯作者：
Carbon, C
中科院分区：
文献类型：
--
作者：
Fantin, B;Joly, V;Carbon, C
我们研究了连续94例社区获得性肺炎患者血液样本中淋巴细胞亚群的演变；这些样本是在住院后72小时和随访时获得的，此时患者被认为已经治愈。与随访计数相比，急性期淋巴细胞计数在总体人群中下降（P < 0.0001）；然而，在每个患者的肺炎过程中，CD4(+) T细胞的百分比保持不变。总体人群的这些变化不受年龄、是否感染人类免疫缺陷病毒（HIV）或病原微生物的显著影响。在68例hiv血清阴性患者中，12例初始CD4(+) T细胞计数为
We investigated the evolution of lymphocyte subsets in blood samples from 94 consecutive patients with community-acquired pneumonia; these samples were obtained 72 hours after hospitalization and at follow-up, when the patients were considered to be cured. Acute-phase lymphocyte counts, as compared with follow-up counts, were decreased in the overall population (P < .0001); however, the percentage of CD4(+) T cells remained unchanged during the course of pneumonia in each patient. These changes that were noted for the overall population were not significantly influenced by age, the presence (or not) of infection with human immunodeficiency virus (HIV), or etiologic microorganisms. Of the 68 HIV-seronegative patients, 12 had initial CD4(+) T cell counts of