Current management of colorectal liver metastases
Current management of colorectal liver metastases
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结直肠肝转移的当前治疗
DOI：
10.2217/crc.13.86
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发表时间：
2014
影响因子：
4.2
通讯作者：
S. Fenwick
中科院分区：
文献类型：
--
作者：
G. Sunderland;D. Dunne;Robert P. Jones;H. Malik;G. Poston;S. Fenwick
结直肠癌在世界范围内很常见，预计在未来几年内会变得更加常见。 肝脏是最常见的转移部位，并且管理越来越复杂。多学科团队管理方法至关重要，并与更好的结果相关。不可切除的肝转移患者仍然可以从肝脏专家的参与中受益，因为联合化疗可以实现高的二次切除率，结合新的生物疗法和肝脏定向局部和局部区域治疗。在围手术期护理中应用增强型恢复模式，以及改善患者手术适应性评估，应有助于减轻老年人群面临的挑战，这些老年人群合并症增加，接受越来越复杂的治疗。
SUMMARY Colorectal cancer is common worldwide and is predicted to become more so in the coming years. The liver is the most common site of metastasis and management is increasingly complex. A multidisciplinary team approach to management is essential, and is associated with better outcomes. Patients with irresectable liver metastases can still benefit from the involvement of a liver specialist, as high secondary resection rates can be achieved with combination chemotherapy, incorporating novel biological therapies and liver-directed local and locoregional treatments. The application of an enhanced recovery model to perioperative care, alongside improvements in the assessment of patient fitness for surgery, should help to mitigate the challenges presented by an older population with increased comorbidity undergoing increasingly complex treatment.
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DOI：
10.1016/s0959-8049(11)71655-0
发表时间：
2011-09
期刊：
Annals of oncology : official journal of the European Society for Medical Oncology
影响因子：
--
作者：
T. Ruers;C. Punt;F. Coevorden;J. Ledermann;G. Poston;W. Bechstein;M. Lentz;M. Mauei;M. Lutz-
通讯作者：
T. Ruers;C. Punt;F. Coevorden;J. Ledermann;G. Poston;W. Bechstein;M. Lentz;M. Mauei;M. Lutz-
影响因子：
9
作者：
Fong, Y;Fortner, J;Blumgart, LH
通讯作者：
Blumgart, LH
影响因子：
158.5
作者：
Kemeny, N;Huang, Y;Fong, YM
通讯作者：
Fong, YM
影响因子：
158.5
作者：
Hurwitz, H;Fehrenbacher, L;Kabbinavar, F
通讯作者：
Kabbinavar, F
影响因子：
51.1
作者：
Nordlinger, Bernard;Sorbye, Halfdan;Gruenberger, Thomas
通讯作者：
Gruenberger, Thomas