Thermo- and pH-responsive star-like polymers synthesized by photoATRP
Thermo- and pH-responsive star-like polymers synthesized by photoATRP
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PhotoATRP 合成的热响应和 pH 响应星状聚合物
DOI：
10.1016/j.polymer.2020.123345
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发表时间：
2021-02-03
期刊：
影响因子：
4.6
通讯作者：
Pan, Xiangcheng
中科院分区：
文献类型：
--
作者：
He, Jianhao;Zhang, Wenjie;Pan, Xiangcheng
通过使用低ppm水平的CuBr 2/三[2-（二甲氨基）乙基]胺（Me 6 TREN）络合物的光诱导原子转移自由基聚合（photoATRP）合成具有受控分子量和低分散性的温度和pH响应性星形嵌段共聚物。星形聚合物PAA-b-P（MEA-co-OEGA（480））在水中表现出下临界溶解温度（LCST）转变，在乙醇中表现出上临界溶解温度（UCST）转变。星形嵌段共聚物的UCST随POEGA侧链比例的增加而减小，而LCST随水溶液pH值的增加而增大。所制备的星形嵌段共聚物具有良好的生物相容性、温和的相转变温度以及在生物体范围内随pH可调的LCST。这些聚合物可以潜在地用于pH响应性和热敏性应用中，并用作纳米反应器以限制无机纳米颗粒的生长。
The thermo and pH-responsive star-like block copolymers are synthesized with controlled molecular weight and low dispersity via photoinduced atom transfer radical polymerization (photoATRP) using a low ppm level of CuBr2 /tris[2-(dimethylamino)ethyl]amine (Me6TREN) complex. The star-like polymers PAA-b-P(MEA-co-OEGA(480)) exhibit both a lower critical solution temperature (LCST) transition in water and the upper critical solution temperature (UCST) transition in ethanol. The UCST decreases with the increase of the POEGA proportion of side chains in the star-like block copolymers, while the LCST increases with the increase of pH in water. The prepared star-like block copolymers have excellent biocompatibility, mild phase transition temperature, and the adjustable LCST with pH in the range of organisms. These polymers could be potentially used in pH-responsive and thermosensitive applications and used as nanoreactors to confine the growth of inorganic nanoparticles.