Aging in elderly: chronological versus photoaging.
Aging in elderly: chronological versus photoaging.
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DOI：
10.4103/0019-5154.100473
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发表时间：
2012-09
影响因子：
1.7
通讯作者：
Malathi M
中科院分区：
文献类型：
--
作者：
Durai PC;Thappa DM;Kumari R;Malathi M
皮肤是衰老变化的窗口，是生物现实。有一个关于亚洲人的各种时间（内在）老化和光老化（外在）变化的研究缺乏。本研究旨在探讨老年人皮肤老化变化及皮肤病的临床模式。这是一项描述性研究，对500名连续的老年人参加皮肤科门诊部。使用Glogau量表对光老化的严重程度进行分级。大多数人群的皮肤类型为IV型和V型。我们的大多数病例（415，83%）有时序老化，无光老化，其余85（17%）例患者沿着时序老化有光老化。常见的皮肤变化，由于时间老化是皮肤变薄，细皱纹，干燥，失去弹性。在我们的研究中，光老化改变如色素沉着不良、雀斑、厚皮肤、深皱纹、黄褐斑、黄绿色皮肤、老年性紫癜、假性星状瘢痕、边缘性肢端角化弹性蛋白病和雀斑样痣的发生率较低。吸烟和长期日晒是加重光老化的危险因素。最常见的皮肤病是瘙痒症，248例（49.6%），其中149例（29.8%）伴有干燥症。接触性皮炎多见于男性。真菌感染常见于女性。脂溢性角化病（253，50.6%）是最常见的良性肿瘤，更常见于男性。皮肤恶性肿瘤在我们的研究人群中不太常见。在IV型皮肤中，光老化变化比时间老化变化不常见。女性的时间变化比男性更频繁，而光老化在男性中更频繁。
Skin is a window to aging changes, a biological reality. There is a dearth of studies regarding the various chronological (intrinsic) aging and photoaging (extrinsic) changes seen in Asians. This study was undertaken to detect the clinical pattern of aging skin changes and dermatoses seen in the elderly. This was a descriptive study conducted on 500 consecutive elderly individuals attending the Dermatology out-patient department. The severity of photoaging was graded using Glogau scale. Most of the population had skin type IV and V. Majority (415, 83%) of our cases had chronological aging without photoaging and the remaining 85 (17%) individuals had photoaging along with chronological aging. The common skin changes due to chronological aging were thin skin, fine wrinkles, xerosis, and loss of elasticity. Photoaging changes such as dyspigmentation, freckles, thick skin, deep wrinkles, melasma, citrine skin, senile purpura, pseudostellate scar, acrokeratoelastoidosis marginalis, and lentigines were less frequent in our study. Smoking and prolonged sun exposure was the risk factors aggravating photoaging. The most common dermatosis was pruritus in 248 (49.6%) individuals, of which 149 (29.8%) had pruritus associated with xerosis. Contact dermatitis was more common in males. Fungal infections were frequently seen in females. Seborrhoeic keratosis (253, 50.6%) was the most common benign neoplasm more commonly seen in males. Cutaneous malignancies were less common in our study population. Photoaging changes were less common than chronological aging changes in skin type IV. Chronological changes were more frequent in females than males, while photoaging was more frequent in males.