Receptors for transferrin and transcobalamin II display segregated distribution on microvilli of leukemia L1210 cells.
Receptors for transferrin and transcobalamin II display segregated distribution on microvilli of leukemia L1210 cells.
复制标题
转铁蛋白和转钴胺素 II 受体在白血病 L1210 细胞的微绒毛上表现出分离分布。
DOI：
10.1016/0006-291x(87)90761-3
复制
发表时间：
1987
影响因子：
3.1
通讯作者：
Jacobsen,DW
中科院分区：
文献类型：
--
作者：
Kishimoto,T;Tavassoli,M;Green,R;Jacobsen,DW
Simultaneous addition of uniform latex particles derivatized with transferrin (0.532 micron) and transcobalamin II (0.345 micron) to leukemia L1210 cells resulted in segregated binding to individual microvilli as demonstrated by scanning electron microscopy. This segregated distribution suggests that individual microvilli are endowed either transferrin or transcobalamin II receptors but not both. Intracellular sorting and segregation of newly synthesized or recycling receptors probably occur prior to expression on the plasmalemma microvilli.
