Rare metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes: A case report and literature review.
Rare metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes: A case report and literature review.
复制标题
鼻咽癌罕见甲状腺转移并发腹部淋巴结转移一例并文献复习
DOI：
10.1097/md.0000000000008373
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发表时间：
2017-11
期刊：
影响因子：
1.6
通讯作者：
Zeng S
中科院分区：
文献类型：
--
作者：
Cai C;Shen H;Liu W;Ma J;Zhang Y;Yin L;Li J;Shen L;Zeng S
鼻咽癌甲状腺转移是罕见的。鼻咽癌转移至甲状腺并继发腹腔淋巴结转移的病例在以往文献中未见报道。我们想分享我们的治疗选择经验。一位27岁男性于2004年8月被诊断为鼻咽非角化性癌。2013年3月，他接受了甲状腺癌根治术，组织学检查显示鼻咽癌转移到甲状腺。2015年4月，18F-FDG-PET/CT扫描和活检显示鼻咽癌转移性腹部淋巴结。一名27岁男性被诊断为鼻咽癌转移到甲状腺，随后转移腹部淋巴结。患者接受同步化疗和放疗治疗鼻咽癌和甲状腺转移。腹腔淋巴结转移者接受化疗。经过6个周期的吉西他滨、顺铂和5-氟尿嘧啶化疗治疗腹部淋巴结转移后，患者目前无症状，病情稳定，生活质量改善。鼻咽癌转移的治疗选择取决于临床疾病程度，必须针对患者个体制定手术和/或放化疗治疗，以改善预后和生活质量。
Thyroid metastasis from nasopharyngeal carcinoma is rare. Metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes hasn’t been reported before. We want to share our experience about the treatment choice. A 27-year-old man was diagnosed with nasopharyngeal nonkeratinizing carcinoma in August 2004. In March 2013 he underwent a thyroid carcinoma radical operation, and histological examination revealed metastasis to the thyroid gland from nasopharyngeal carcinoma. An 18F-FDG-PET/CT scan and biopsy showed metastatic abdominal lymph nodes of nasopharyngeal carcinoma in April 2015. A 27-year-old man was diagnosed with metastasis of nasopharyngeal carcinoma to the thyroid gland with subsequent metastatic abdominal lymph nodes. The patient was treated with concurrent chemotherapy and radiotherapy for nasopharyngeal carcinoma and metastasis to the thyroid gland. The metastases to the abdominal lymph nodes received chemotherapy. After 6 cycles of chemotherapy with gemcitabine, cisplatin, and 5-fluorouracil for metastasis to the abdominal lymph nodes, the patient is currently asymptomatic with stable disease and improved quality of life. The treatment choice for metastasis of nasopharyngeal carcinoma depends on the clinical disease extent, and surgery and/or chemo-radiation therapy must be drafted to the individual patient in order to improve the prognosis and quality of life.