Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults: Fourth edition
Guidelines of the International Headache Society for controlled trials of acute treatment of migraine attacks in adults: Fourth edition
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DOI：
10.1177/0333102419828967
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发表时间：
2019-05-01
期刊：
影响因子：
4.9
通讯作者：
Mandrekar, Jay
中科院分区：
文献类型：
--
作者：
Diener, Hans-Christoph;Tassorelli, Cristina;Mandrekar, Jay
临床试验的质量是头痛疾病治疗证据基础的重要组成部分。1991年，国际头痛协会临床试验常务委员会制定并出版了第一版偏头痛药物对照试验指南。头痛医学的科学和临床发展分别在2000年和2012年推出了第二版和第三版。目前的《准则》第四版保留了前几版的结构和许多内容。然而，它也包含了第三版之后发表的临床试验的证据，以及与监管机构，制药和设备制造商以及患者协会会议的反馈。其最后形式反映了委员会的集体专门知识和判断。这些更新的建议和评论旨在满足该协会的持续目标，即为偏头痛发作急性治疗的随机对照试验的开展和报告提供一种现代化、标准化和循证方法。
The quality of clinical trials is an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for controlled trials of drugs in migraine. Scientific and clinical developments in headache medicine led to second and third editions in 2000 and 2012, respectively. The current, fourth edition of the Guidelines retains the structure and much content from previous editions. However, it also incorporates evidence from clinical trials published after the third edition as well as feedback from meetings with regulators, pharmaceutical and device manufacturers, and patient associations. Its final form reflects the collective expertise and judgement of the Committee. These updated recommendations and commentary are intended to meet the Society's continuing objective of providing a contemporary, standardized, and evidence-based approach to the conduct and reporting of randomised controlled trials for the acute treatment of migraine attacks.