Digital Breast Tomosynthesis: Observer Performance Study
Digital Breast Tomosynthesis: Observer Performance Study
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DOI：
10.2214/ajr.08.2031
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发表时间：
2009-08-01
影响因子：
5
通讯作者：
Bandos, Andriy I.
中科院分区：
文献类型：
--
作者：
Gur, David;Abrams, Gordon S.;Bandos, Andriy I.
目标。本研究的目的是在一项回顾性观察性研究中，比较全视野数字乳腺摄影(FFDM)和数字乳腺断层扫描的诊断性能。8名经验丰富的放射科医生解读了125项选定检查的图像，其中35项检查证实患有癌症，90名没有发现癌症。4种显示条件包括单独的FFDM、11个低剂量投影、重建的数字乳腺断层合成图像以及FFDM和数字乳腺断层合成图像的组合显示模式。观察者使用筛选BI-RADS评价表和自由反应接收器操作特征范例对检查进行评分。观察者的表现水平被衡量为促使患者召回进行进一步诊断评估的检查的比例。结果以真阳性分数和假阳性分数表示。比较不同获取方式和不同阅读方式的绩效水平。观察和解释检查的时间也被评估。结果：联合使用数字化乳房断层扫描和ffdm可以使非癌症检查的召回率降低30%，这将导致回忆起是否单独使用ffm(对于参与的放射科医生来说p<；0.0001，在普通放射科医生的背景下p=0.047)。仅使用数字乳房断层合成术也倾向于降低召回率，平均为10%，尽管观察到的下降在统计学上并不显著(对于参与研究的放射科医生来说，p=0.09)。没有令人信服的证据表明单独使用数字乳房断层合成术或与FFDM联合使用可以显著提高敏感度。结论：使用数字乳房断层成像术进行乳房成像可能会导致召回率大幅下降。
OBJECTIVE. The purpose of this study was to compare in a retrospective observer study the diagnostic performance of full-field digital mammography (FFDM) with that of digital breast tomosynthesis.MATERIALS AND METHODS. Eight experienced radiologists interpreted images from 125 selected examinations, 35 with verified findings of cancer and 90 with no finding of cancer. The four display conditions included FFDM alone, 11 low-dose projections, reconstructed digital breast tomosynthesis images, and a combined display mode of FFDM and digital breast tomosynthesis images. Observers rated examinations using the screening BI-RADS rating scale and the free-response receiver operating characteristic paradigm. Observer performance levels were measured as the proportion of examinations prompting recall of patients for further diagnostic evaluation. The results were presented in terms of true-positive fraction and false-positive fraction. Performance levels were compared among the acquisitions and reading modes. Time to view and interpret an examination also was evaluated.RESULTS. Use of the combination of digital breast tomosynthesis and FFDM was associated with 30% reduction in recall rate for cancer-free examinations that would have led to recall if FFDM had been used alone (p < 0.0001 for the participating radiologists, p = 0.047 in the context of a generalized population of radiologists). Use of digital breast tomosynthesis alone also tended to reduce recall rates, an average of 10%, although the observed decrease was not statistically significant (p = 0.09 for the participating radiologists). There was no convincing evidence that use of digital breast tomosynthesis alone or in combination with FFDM results in a substantial improvement in sensitivity.CONCLUSION. Use of digital breast tomosynthesis for breast imaging may result in a substantial decrease in recall rate.